Results 11 to 20 of about 50,720 (250)

Development of a mechanism of action-reflective, dual target cell-based reporter bioassay for a bispecific monoclonal antibody targeting human CTLA-4 and PD-1

mAbs, 2021
T-cell-mediated immunotherapy has generated much excitement after the success of therapeutic biologics targeting immune checkpoint molecules. Bispecific antibodies (BsAbs) that recognize two antigen targets are a fast-growing class of biologics offering ...
Weimin Chen, Madhu Pandey, Hong Sun, Andrea Rolong, Mingyan Cao, Dengfeng Liu, Jihong Wang, Lingmin Zeng, Alan Hunter, Shihua Lin   +9 more
doaj   +1 more source

Correction to: Dose–response relationship of pulmonary disorders by inhalation exposure to cross-linked water-soluble acrylic acid polymers in F344 rats

Particle and Fibre Toxicology, 2022
Graphic ...
Tomoki Takeda, Shotaro Yamano, Yuko Goto, Shigeyuki Hirai, Yusuke Furukawa, Yoshinori Kikuchi, Kyohei Misumi, Masaaki Suzuki, Kenji Takanobu, Hideki Senoh, Misae Saito, Hitomi Kondo, George Daghlian, Young-Kwon Hong, Yasuhiro Yoshimatsu, Masanori Hirashima, Yoichiro Kobashi, Kenzo Okamoto, Takumi Kishimoto, Yumi Umeda   +19 more
doaj   +1 more source

Exposure of Rats to Multi-Walled Carbon Nanotubes: Correlation of Inhalation Exposure to Lung Burden, Bronchoalveolar Lavage Fluid Findings, and Lung Morphology

Nanomaterials, 2023
To evaluate lung toxicity due to inhalation of multi-walled carbon nanotubes (MWCNTs) in rats, we developed a unique MWCNT aerosol generator based on dry aerosolization using the aerodynamic cyclone principle.
Tatsuya Kasai, Shoji Fukushima
doaj   +1 more source

Humoral cross-reactivity towards SARS-CoV-2 in young children with acute respiratory infection with low-pathogenicity coronaviruses

Journal of Clinical Virology Plus, 2022
Background: SARS-CoV-2 infection in children frequently leads to only asymptomatic and mild infections. It has been suggested that frequent infections due to low-pathogenicity coronaviruses in children, impart immunity against SARS-CoV-2 in this age ...
Nitin Dhochak, Tanvi Agrawal, Heena Shaman, Naseem Ahmed Khan, Prawin Kumar, Sushil K. Kabra, Guruprasad R. Medigeshi, Rakesh Lodha   +7 more
doaj   +1 more source

Neutralizing antibodies from prior exposure to dengue virus negatively correlate with viremia on re-infection

Communications Medicine, 2023
Background India is hyperendemic to dengue and over 50% of adults are seropositive. There is limited information on the association between neutralizing antibody profiles from prior exposure and viral RNA levels during subsequent infection.
Anbalagan Anantharaj, Tanvi Agrawal, Pooja Kumari Shashi, Alok Tripathi, Parveen Kumar, Imran Khan, Madhu Pareek, Balwant Singh, Chitra Pattabiraman, Saurabh Kumar, Rajesh Pandey, Anmol Chandele, Rakesh Lodha, Stephen S. Whitehead, Guruprasad R. Medigeshi   +14 more
doaj   +1 more source

Metronidazole Bioassay [PDF]

Antimicrobial Agents and Chemotherapy, 1976
Urine from patients receiving metronidazole [1-(2-hydroxyethyl)-2-methyl-5-nitromidazole] orally or per vagina were subjected to paper chromatographic fractionation and examined for anticlostridial activity. Unmodified metronidazole and several metabolites were detected.
W T, Speck, A B, Stein, H S, Rosenkranz
openaire   +2 more sources

Bioassay- and Chemistry-Guided Isolation of Scalemic Caged Prenylxanthones from the Leaves of Garcinia bracteata

, 2018
With bioassay- and chemistry-guided fractionation, seven new caged prenylxanthones including two scalemic mixtures, epiisobractatin (1), 13-hydroxyisobractatin (2), 13-hydroxyepiisobractatin (3), 8-methoxy-8,8a-dihydrobractatin (4), 8-ethoxy-8,8a ...
Yue-Tong Wang (4992881), Hui-Ming Hua (534567), Da-Hong Li (770554), Xin-Yu Li (1378743), Yong-Kui Jing (1546174), Zhan-Lin Li (534568), Yue-Hu Pei (737972), Sheng-Ge Li (4992878), Jiao Bai (737971), Sheng-Li Niu (1559965)   +9 more
core   +4 more sources

Preparation of Monoclonal Antibody and Development of Indirect Competitive Enzyme-Linked Immunosorbent Assay and Fluorescence-Linked Immunosorbent Assay for Detecting 3-Amino-5-methylmorpholino-2-oxazolidinone (AMOZ) in Edible Animal Tissue

Molecules, 2021
To monitor the illegal used of furaltadone, a highly sensitive indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) and fluorescence-linked immunosorbent assay (FLISA) based on a monoclonal antibody (mAb) were developed for the detection of ...
Yong Xie, Yarong Wang, Xueling Yan, Lu Gan, Tao Le   +4 more
doaj   +1 more source

How important is the angle of tilt in the WHO cone bioassay? [PDF]

, 2016
The World Health Organization (WHO) cone bioassay plays an integral role in the evaluation of the efficacy of long-lasting insecticidal nets as well as insecticides used in indoor residual spraying.
Müller, Pie, Pie Müller, Owusu, Henry F., Henry F. Owusu   +3 more
core   +1 more source

Bioassay for Miconazole [PDF]

Antimicrobial Agents and Chemotherapy, 1977
A radial diffusion bioassay for miconazole, which employs Candida stellatoidea as the indicator organism, is described. Results from three patients treated with the drug are presented.
A, Espinel-Ingroff, S, Shadomy, J F, Fisher   +2 more
openaire   +2 more sources