Results 161 to 170 of about 719,874 (416)

Targeting glutamate metabolism in melanoma [PDF]

arXiv, 2019
The glutamate metabotropic receptor 1 (GRM1) drives oncogenesis when aberrantly activated in melanoma and several other cancers. Metabolomics reveals that patient-derived xenografts with GRM1-positive melanoma tumors exhibit elevated plasma glutamate levels associated with metastatic melanoma in vivo. Stable isotope tracing and GCMS analysis determined
arxiv  

Bioavailability to Rats of Zinc, Magnesium and Calcium in Casein-, Egg- and Soy Protein-Containing Diets [PDF]

, 1979
Richard Forbes, K. Weingärtner, Helen M. Parker, Roma R. Bell, John W. Erdman   +4 more
openalex   +1 more source

Iron bioavailability in two commercial cultivars of wheat: a comparison between wholegrain and white flour and the effects of nicotianamine and 2'-deoxymugineic acid on iron uptake into Caco-2 cells [PDF]

, 2014
Iron bioavailability in unleavened white and wholegrain bread made from two commercial wheat varieties was assessed by measuring ferritin production in Caco-2 cells.
Anna A. Wawer, Ariza-Nieto M., Beta T., Bouis H. E., Cakmak I., Cheng L., Eagling T., Engle-Stone R., Fang-Jie Zhao, Fernandez-Orozco R., Garcia M. N., Glahn R. P., Glahn R. P., Glahn R. P., Glahn R. P., Glahn R. P., Haas J. D., Higuchi K., Hurrell R., Kalgaonkar S., Lee S., Lipschitz D. A., Mattila P., McLean E., Mino Y., Morris E. R., Ortiz-Monasterio J. I., Oury F.-X., Persson D. P., Peter R. Shewry, Qureshi I. M., Sandberg A. S., Schlemmer U., Scientific Advisory Committee on Nutrition, Shewry P. R., Shojima S., Susan J. Fairweather-Tait, Thavarajah D., Thompson B., Thompson B. A. V., Tristan Eagling, Velu G., Wawer A. A., White P. J., Yun S., Zhang Y., Zhao F. J., Zheng L.   +47 more
core   +1 more source

The Problem of Curcumin and Its Bioavailability: Could Its Gastrointestinal Influence Contribute to Its Overall Health-Enhancing Effects?

Advances in Nutrition, 2018
Curcumin, from the spice turmeric, exhibits anti-inflammatory, antioxidant, anticancer, antiviral, and neurotrophic activity and therefore holds promise as a therapeutic agent to prevent and treat several disorders. However, a major barrier to curcumin's
A. Lopresti
semanticscholar   +1 more source

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

Advanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle, Dhruv Menon, João Conniot, Jon Ostolaza‐Paraiso, Sergio Mercado, Jhenifer Oliveira, Xu Chen, Bárbara B. Mendes, João Conde, David Fairen‐Jimenez   +9 more
wiley   +1 more source

Effects of root exudates on the sorption of polycyclic aromatic hydrocarbons onto biochar

Environmental Pollutants & Bioavailability, 2019
The effect of oxalic acid on phenanthrene sorption was varied from that on pyrene sorption. 1.0 mg L-1 of oxalic acid inhibited phenanthrene sorption, whereas 20, 50 and 100 mg L-1 of oxalic acid enhanced the sorption.
Xiaona Li, Yang Song, Yongrong Bian, Fang Wang, Chenggang Gu, Xinglun Yang, Xin Jiang   +6 more
doaj   +1 more source

Direct measurement of propranolol bioavailability during accumulation to steady‐state. [PDF]

, 1978
AJ Wood, K. Carr, R. E. Vestal, S. E. Belcher, G R Wilkinson, DG Shand   +5 more
openalex   +1 more source

Bioavailability of Tea Catechins and Its Improvement

Molecules, 2018
Many in vitro studies have shown that tea catechins had vevarious health beneficial effects. However, inconsistent results between in vitro and in vivo studies or between laboratory tests and epidemical studies are observed.
Zhuo-Yu Cai, Xu-Min Li, Jin-Pei Liang, Li-Ping Xiang, Kai-Rong Wang, Yunlong Shi, Rui Yang, Meng Shi, J. Ye, Jian-Liang Lu, Xinqiang Zheng, Yuerong Liang   +11 more
semanticscholar   +1 more source

Carbon Dot‐Linked Hydrogel for TAMs Transform: Spatiotemporal Manipulation to Reshape Tumor Microenvironment

Advanced Materials, EarlyView.
The CDs crosslinked egg white hydrogel loaded with lipopolysaccharide (LPS) and CA170 (TTF‐L‐C) can realize spatiotemporal tumor‐associated macrophages (TAMs) transformation from multi‐level dimensions, including spatial recruitment, cell phenotype reprogramming, and immune checkpoint molecule blockade.
Lingyun Li, Jun Wu, Xue Wu, Zhenjian Li, Xianming Zhang, Zekun Yan, Yingqi Liang, Caishi Huang, Songnan Qu   +8 more
wiley   +1 more source

Spatial distribution of total halogenated organic compounds (TX), adsorbable organic halogens (AOX), and heavy metals in wetland soil irrigated with pulp and paper wastewater

Chemical Speciation & Bioavailability, 2017
Long-term irrigation using wastewater from paper industry may cause seriously problems to the receiving soil. This work surveyed and monitored the soil quality of a wastewater irrigation wetland system in Yancheng City, Jiangsu Province in China in 2014 ...
Liqiang Cui, Tianming Chen, Cheng Ding, Zhaoxia Li, Jinlong Yan, Yang Liu, Xian Niu, Aihui Chen, Wenjun Yang   +8 more
doaj   +1 more source