Results 251 to 260 of about 61,606 (334)

The cervico‐vaginal DNA methylation WID‐qEC test: An epigenetic marker associated with ovarian cancer in the absence of endometrial and cervical cancer

International Journal of Cancer, EarlyView.
What's New? The DNA methylation‐based WID‐qEC test has been validated for the accurate detection of endometrial and cervical cancers using cervico‐vaginal samples. However, a small proportion of women test positive despite the absence of these cancers. This study explored the associated biological and clinical characteristics to inform potential follow‐
Elisa Redl, Chiara Herzog, Charlotte Vavourakis, James Barrett, Allison Jones, Iona Evans, Daniel Reisel, Ranjit Manchanda, Line Bjørge, Michal Zikan, David Cibula, Twana Alkasalias, Angelique Flöter Rådestad, Kristina Gemzell‐Danielsson, Louis Dubeau, Nicola MacDonald, Davor Jurkovic, Nora Pashayan, Martin Widschwendter   +18 more
wiley   +1 more source

PERSIAN cohort biobank: creating a large-scale national resource for biomedical research in Iran. [PDF]

BMC Public Health
Shayanrad A, Mousavi S, Eftekhari S, Roshandel G, Irilouzadian R, Poustchi H, Malekzadeh R.   +6 more
europepmc   +1 more source

Consent for Biobanking [PDF]

, 2008
Laurie, Graeme
core  

Detection of recurrent endometrial cancer via DNA methylation analysis of cervicovaginal self‐samples and urine

International Journal of Cancer, EarlyView.
What's New? Post‐treatment surveillance for endometrial cancer aims to detect recurrence early, potentially improving outcome. Emerging evidence suggests that DNA methylation analysis of self‐collected cervicovaginal and urine samples is a promising approach.
Annick J. Nouwens, Mirte Schaafsma, Nienke E. van Trommel, Jenneke C. Kasius, Renske D. M. Steenbergen, Maaike C. G. Bleeker   +5 more
wiley   +1 more source

Long-Term Biobanked Dental Pulp Stem Cells Retain Angiogenic Potential for Vascularised Tissue Engineering-Laboratory Investigation. [PDF]

Int Endod J
Yamada S, Holomkova K, Johansen Å, Kadousaraei MJ, Al-Sharabi N, Torelli F, Pagella P, Volponi AA, Egusa H, Fristad I, Mustafa K.   +10 more
europepmc   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Estimating the use of biological samples in Finnish biobanks and hospital collections. [PDF]

Eur J Hum Genet
Tupasela A, Southerington T, Mäkelä J, Kallio L, Perälä M, Kosma VM, Mannermaa A, Jokela T, Pitkänen K, Kontro M, Vesterinen T, Punkka E, Knopp T, Ruddock M, Serpi R, Moilanen AM, Viiri L, Siltanen S, Makkonen E, Ingalsuo P.   +19 more
europepmc   +1 more source

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng, Xiao Han, Congquan Wu, Qiaowen Lu, Shujun Gao   +4 more
wiley   +1 more source

Causal effects of reproductive traits on cognitive function: A two‐sample and multivariable mendelian randomization study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Potential associations between reproductive traits and cognitive function have been discovered; however, the results are inconsistent, and the causalities are unclear. This study utilized Mendelian randomization (MR) analysis to assess the causal impact of reproductive traits on cognitive function.
Xia Wang, Yunyun Guo
wiley   +1 more source

Investigate the Effects of Preeclampsia Severity, Race and Fetal Sex on Subsequent Maternal Complications Using EHR Data From Over 100,000 Pregnancies

iMetaMed, EarlyView.
We examined Preeclampsia‐associated comorbidities in the UM Discovery Cohort using confounder‐adjusted models, validated across UK Biobank, Cedars‐Sinai, and Vanderbilt, revealing condition‐specific risks supported by OR estimates and KM survival curves.
Xiaotong Yang, Haoming Zhu, Leyang Tao, Raelynn Chen, Jui‐Hsuan Chang, Zhiping P. Wang, Elizabeth S. Langen, Ashley M. Hesson, Cosmin A. Bejan, Ruowang Li, Lana X. Gamire   +10 more
wiley   +1 more source