Results 261 to 270 of about 61,606 (334)

Biobanking and consent to future biospecimen use among adults enrolled in SWOG trials from 2000 to 2024. [PDF]

open access: yesBlood Cancer J
Olivieri DJ   +6 more
europepmc   +1 more source

Ribosomal RNA operon copy number: A trait‐informed framework to close the microbial cultivation gap

open access: yesiMetaOmics, EarlyView.
The vast majority of microbes remain uncultured, constraining functional validation and limiting microbiome‐based applications. We show that ribosomal RNA operon (rrn) copy number—a stable, phylogenetically conserved genomic trait—is strongly correlated with cultivation outcomes across ecosystems.
Yuxiao Huang   +8 more
wiley   +1 more source

Biorepositories For Global Rare Disease Research: A Narrative Review. [PDF]

open access: yesCurr Rheumatol Rep
Pellico MR   +6 more
europepmc   +1 more source

Exploring the Link Between Psoriasis and Genetic Predictors of Cardiac Magnetic Resonance Traits: A Bidirectional Mendelian Randomization Study

open access: yesiNew Medicine, EarlyView.
ABSTRACT Psoriasis is a chronic autoimmune disease characterized by systemic inflammation and skin involvement, affecting millions of individuals worldwide. However, few studies have evaluated whether psoriasis and cardiac magnetic resonance imaging (CMR) traits share a common genetic basis.
Junlin Yang   +8 more
wiley   +1 more source

Evaluating the use of biobanked urine specimens for human urobiome studies. [PDF]

open access: yesMicrobiol Spectr
Mukherjee SD   +5 more
europepmc   +1 more source

Socioeconomic Status Modifies the Risk of Gastric Cancer Through Metabolomic Signature: Evidence From a Prospective Cohort Study

open access: yesiNew Medicine, EarlyView.
ABSTRACT The role of metabolites in the association between socioeconomic status (SES) and gastric cancer remains unclear. This study seeks to elucidate the role of metabolomics in the association between SES and gastric cancer, as well as to explore potential interactions between metabolic signatures and polygenic risk score (PRS) in the context of ...
Shiyin Meng   +8 more
wiley   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

open access: yesInterdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang   +6 more
wiley   +1 more source

Influence of Isolation Techniques on the Quality of Plasma Samples: Implications for Cancer Biobanking. [PDF]

open access: yesInt J Mol Sci
Piccotti F   +10 more
europepmc   +1 more source

Exploring Uric Acid to HDL Ratio as a Long‐Term Biomarker for Diabetes Mellitus

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study explores the predictive value of the serum uric acid to HDL cholesterol ratio (UHR) for diabetes mellitus (DM) using data from the decade‐long MASHAD cohort. Elevated UHR levels were significantly associated with increased DM risk, with gender‐specific thresholds identified through ROC analysis. These findings support UHR as a promising long‐
Rana Kolahi   +9 more
wiley   +1 more source

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