Results 61 to 70 of about 66,316 (259)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Pengaruh Bambu Untuk Pipa Distribusi Air Minum Terhadap Kualitas Air (Studi Kasus Distribusi Air Minum Di Paweden, Karangkobar, Banjarnegara)

open access: yesDinamika Rekayasa, 2005
This research was aimed to know bamboo influence to the physical, and chemical characteristic, and water quality. Parameters observed are temperature, color, taste, odor, pH,DO (dissolved oxygen), BOD (biochemical oxygen demand) and COD (biochemical ...
Nastain   +2 more
doaj  

Modelling biochemical oxygen demand using improved neuro-fuzzy approach by marine predators algorithm. [PDF]

open access: yesEnviron Sci Pollut Res Int, 2023
Adnan RM   +6 more
europepmc   +1 more source

biochemical (biological) oxygen demand

open access: yes, 2014
Citation: 'biochemical (biological) oxygen demand' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.B00653 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

A SOFTWARE SENSOR FOR IN-SITU MONITORING OF THE 5-DAY BIOCHEMICAL OXYGEN DEMAND

open access: yesRudarsko-geološko-naftni Zbornik, 2018
Due to the time-consuming procedure for determining the 5-day biochemical oxygen demand (BOD5), the present study developed two software sensors based on artificial intelligence techniques to estimate this indicator instantaneously.
Rana Kasem   +3 more
doaj   +1 more source

Rapid Determination Of Biochemical Oxygen Demand

open access: yes, 2009
Biochemical Oxygen Demand (BOD) is a measure of the oxygen used in bacteria mediated oxidation of organic substances in water and wastewater. Theoretically an infinite time is required for complete biochemical oxidation of organic matter, but the measurement is made over 5-days at 20 0C or 3-days at 27 0C test period with or without dilution ...
Mayur Milan Kale, Indu Mehrotra
openaire   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

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