Results 61 to 70 of about 1,513,760 (300)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Statistical Significance of Correlations Between Biochemical and Agronomic Traits of Selected Sub-Lines.

open access: yes, 2016
Statistical Significance of Correlations Between Biochemical and Agronomic Traits of Selected Sub-Lines.
Goran Stankovic (3390872)   +6 more
core   +1 more source

Genetic diversity of sugarcane (Saccharum spp.) genotypes based on agro-morphological and biochemical traits

open access: yes, 2023
Knowledge of genetic diversity is essential for the effective planning of breeding experiments and successful development of an improved variety. Therefore, this study was aimed at assessing the genetic diversity of 196 sugarcane genotypes.
Belay Tolera (15308570)   +2 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Clustering of isolated A. acidoterrestris strains considering some biochemical traits.

open access: yes, 2015
Clustering of isolated A. acidoterrestris strains considering some biochemical traits.
Maria Rosaria Corbo (816183)   +5 more
core   +1 more source

Evaluation of Salinity Tolerance Potentials of Two Contrasting Soybean Genotypes Based on Physiological and Biochemical Responses

open access: yesPlants
Salinity stress is a major abiotic constraint limiting soybean (Glycine max L.) productivity in saline–alkali soils; however, the physiological and biochemical mechanisms underlying genotypic tolerance remain poorly understood.
Mawia Sobh   +4 more
doaj   +1 more source

Principal component analysis of tomato genotypes based on some morphological and biochemical quality indicators [PDF]

open access: yesRatarstvo i Povrtarstvo, 2012
This study investigates variability of tomato genotypes based on morphological and biochemical fruit traits. Experimental material is a part of tomato genetic collection from Institute of Filed and Vegetable Crops in Novi Sad, Serbia.
Glogovac Svetlana   +7 more
doaj   +1 more source

Diversity of the Morphometric and Biochemical Traits of Allium cepa L. Varieties. [PDF]

open access: yesPlants (Basel)
Several Allium cepa L. varieties, representing a versatile set of vegetables widely utilized by consumers, are appreciated for their bioactive properties, including antimicrobial, anticarcinogenic, and antioxidant capacities. The aim of this study is to compare the morphometric characteristics and biochemical profiles of four cultivars of A.
Arena D   +7 more
europepmc   +6 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

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