Results 221 to 230 of about 2,285,544 (373)
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
REVISION OF THE BIOCHEMISTRY COURSE CONTENTS IN MEDICINE AND DENTISTRY FIELDS
Durdi Qujeq, Iman Jahanian, Mohsen Tatar
openalex +1 more source
Publisher Correction: Piezo1 regulates meningeal lymphatic vessel drainage and alleviates excessive CSF accumulation. [PDF]
Choi D +15 more
europepmc +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
The Biochemistry of Plants: A Comprehensive Treatise [PDF]
Barry Halliwell +4 more
openalex +1 more source
From biomarker to bedside? A critical commentary on ischemia-modified albumin in preeclampsia. [PDF]
Varikasuvu SR.
europepmc +1 more source

