Results 21 to 30 of about 57,214 (296)

Novel Antifungal Scaffold Targeting Tubulin Overcomes Sclerotinia Sclerotiorum Resistance

Advanced Science, EarlyView.
Addressing pesticide resistance, novel chromone‐acylhydrazone hybrids targeting fungal tubulin are synthesized. Compound G24 potently inhibited S. sclerotiorum (EC50 = 0.21µg mL−1) and demonstrated enhanced field performance via microencapsulation, offering a sustainable strategy against resistance and for global food security.
Lihui Shao, Xianqun Hu, Ying Wu, Xiang Zhou, Bo Zhang, Song Yang   +5 more
wiley   +1 more source

A Novel Protein Sourced from Chinese Medicine Residue for Golden Pompano Feed: Endothelium Corneum Gigeriae Galli Residue (ECGGR)

Aquaculture Nutrition
Fishmeal is an important protein source in aquafeed. However, due to the limited natural resources, fishmeal is in short supply, resulting in a price surge for fishmeal.
Ziqiao Wang, Rong Yao, Xuanshu He, Xin Cui, Zhihong Liao, Yantao Liu, Hanlin Wei, Zhenxiao Zhuang, Mengdie Chen, Jin Niu   +9 more
doaj   +1 more source

Genomic insight into the scale specialization of the biological control agent Novius pumilus (Weise, 1892)

BMC Genomics, 2022
Background Members of the genus Novius Mulsant, 1846 (= Rodolia Mulsant, 1850) (Coleoptera, Coccinellidae), play important roles in the biological control of cotton cushion scale pests, especially those belonging to Icerya.
Xue-Fei Tang, Yu-Hao Huang, Hao-Sen Li, Pei-Tao Chen, Huan-Ying Yang, Yuan-Sen Liang, Xue-Yong Du, Zhen-Hua Liu, En-Feng Li, Yu-Chen Yang, Hong Pang   +10 more
doaj   +1 more source

Poly(A)-Binding Protein Cytoplasmic 1 Inhibits Porcine Epidemic Diarrhea Virus Replication by Interacting with Nucleocapsid Protein

Viruses, 2022
Porcine epidemic diarrhea virus (PEDV) is the etiological agent of porcine epidemic diarrhea (PED) characterized by vomit, watery diarrhea, dehydration and high mortality.
Tingting Wu, Xiaona Wei, Shumei Zheng, Gaoli She, Zhenling Han, Zhichao Xu, Yongchang Cao, Chunyi Xue   +7 more
doaj   +1 more source

HMGB2–RAD21 Axis Promotes Fibro/Adipogenic Progenitor Proliferation and Regulates Fat Infiltration

Advanced Science, EarlyView.
This study constructed the first developmental atlas of embryonic skeletal muscle fibro/adipogenic progenitors (FAPs) and identified an HMGB2+ FAPs subpopulation that regulates FAP pool size and muscle homeostasis. HMGB2 directly targets the RAD21 promoter, and its knockout significantly reduces FAP numbers, thereby lowering the potential for ...
Xian Tong, Ziyun Liang, Tianqi Duo, Liping Pan, Qi Zhu, Jiete Liang, Xianyao Luo, Qingcai Feng, Rong Xu, Yihao Liu, Xu Chen, Luxi Chen, Xiaohong Liu, Yaosheng Chen, Delin Mo   +14 more
wiley   +1 more source

Comparative Assessment of Synthetic and Algal-Derived Astaxanthin Supplementation on Growth Traits, Lipid Homeostasis, and Liver Well-Being in High-Fat Diet-Fed Trachinotus ovatus

Aquaculture Nutrition
While aquaculture often relies on excessive lipid intake to bolster fish growth and cut feed expenses, this practice can also result in hepatic fat accumulation, inflammatory responses, oxidative damage, and immune system malfunctions in aquatic ...
Yucai Guo, Haiqi Pu, Sihan Lin, Baoyang Chen, Anqi Chen, Mingyan Huai, Wei Zhao, Jin Niu   +7 more
doaj   +1 more source

Principles for Rigorous Design and Application of Synthetic Microbial Communities

Advanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang, Minyu Jing, Lihui Lyu, Li Nie, Xihui Xu, Ru Sun, Xiyuan Xu, Siyu Chen, Shuobing He, Yumeng Zhang, Ping Huang, Weijie Luo, Jiaojiao Liang, Guifeng Gao, Kunkun Fan, Teng Yang, Liyan Zhang, Xiao Fu, Sarah M. Allard, Jack A. Gilbert, Jiabao Zhang, Haiyan Chu   +21 more
wiley   +1 more source

Effects of Lysophospholipid on Growth Performance, Hepatopancreas Health, and Intestinal Microbiome of Litopenaeus vannamei in Low-Fishmeal Diet

Aquaculture Nutrition
A 56-day culture experiment was conducted to assess the effects of lysophospholipid added to a low-fishmeal diet on growth performance, hepatopancreas health, and intestinal microbiome of Litopenaeus vannamei. Three experimental diets were set up in this
An-Qi Chen, Bao-Yang Chen, Jian Zhong, Zhi-Hong Liao, Xuan-Shu He, Si-Han Lin, Chuan-Ji Fang, Ning Li, Wei Zhao, Jin Niu   +9 more
doaj   +1 more source

Architecture of the baculovirus nucleocapsid revealed by cryo-EM

Nature Communications, 2023
Baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV) has been widely used as a bioinsecticide and a protein expression vector. Despite their importance, very little is known about the structure of most baculovirus proteins.
Xudong Jia, Yuanzhu Gao, Yuxuan Huang, Linjun Sun, Siduo Li, Hongmei Li, Xueqing Zhang, Yinyin Li, Jian He, Wenbi Wu, Harikanth Venkannagari, Kai Yang, Matthew L. Baker, Qinfen Zhang   +13 more
doaj   +1 more source

Higher‐Level Structural Classification of Pseudomonas Cyclic Lipopeptides through Their Bioactive Conformation

Advanced Science, EarlyView.
Solution structures of a series of cyclic lipodepsipeptides from Pseudomonas reveal that these specialized metabolites adopt left‐handed alpha helical conformations of only two types, being either ‘stapled’ or ‘catch‐pole’ helix. The particular modular distribution of the biosynthetic gene clusters is found to determine the extent of their conserved ...
Benjámin Kovács, Durga Prasad, Vic De Roo, Matthias Vanheede, Penthip Muangkaew, Annemieke Madder, Monica Höfte, René De Mot, Niels Geudens, José C. Martins   +9 more
wiley   +1 more source