Results 241 to 250 of about 71,676 (307)

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

open access: yesAdvanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza   +19 more
wiley   +1 more source

Piperazine‐Functionalized Nanoparticles Enable Oral Insulin Delivery in Obese Mice

open access: yesAdvanced Science, EarlyView.
ABSTRACT Biologics have gained prominence as a rapidly advancing therapeutic modality for a diverse spectrum of medical conditions. Nonetheless, they are predominantly administered parenterally due to poor absorption through the gastrointestinal tract. Additionally, repeated injections of biologics such as insulin cause injection pain, leading to dose ...
Yuxue Cao   +14 more
wiley   +1 more source

Development of mycelium-reinforced dialdehyde cellulose-polyvinyl alcohol composites for emerging high-performance sustainable materials. [PDF]

open access: yesSynth Syst Biotechnol
Petchsong P   +5 more
europepmc   +1 more source

Advances in New Alloys, Polymers and Composites for Biomedical Applications. [PDF]

open access: yesMaterials (Basel)
Gil J   +6 more
europepmc   +1 more source

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