We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza +19 more
wiley +1 more source
Piperazine‐Functionalized Nanoparticles Enable Oral Insulin Delivery in Obese Mice
ABSTRACT Biologics have gained prominence as a rapidly advancing therapeutic modality for a diverse spectrum of medical conditions. Nonetheless, they are predominantly administered parenterally due to poor absorption through the gastrointestinal tract. Additionally, repeated injections of biologics such as insulin cause injection pain, leading to dose ...
Yuxue Cao +14 more
wiley +1 more source
Development of mycelium-reinforced dialdehyde cellulose-polyvinyl alcohol composites for emerging high-performance sustainable materials. [PDF]
Petchsong P +5 more
europepmc +1 more source
Rosin-Modified Microcrystalline Cellulose for Enhancing Polylactic Acid-Based Composites with Good Interfacial Compatibility and Mechanical Performance. [PDF]
Zhao F +8 more
europepmc +1 more source
Beyond the Material: Engineering Sustainable Soft Robots and Electronics. [PDF]
Hartmann F, Kaltenbrunner M.
europepmc +1 more source
Biodegradable polymer-wood flour composites: main properties and biodegradability
Scaffaro, R, LA MANTIA, Fp, LO RE, G
openaire +1 more source
Advances in New Alloys, Polymers and Composites for Biomedical Applications. [PDF]
Gil J +6 more
europepmc +1 more source
Advances in Biomass-Derived and Biodegradable Polymer Materials: Synthesis and Application. [PDF]
Lee J.
europepmc +1 more source
Exploring morphological and thermal characteristics of chitosan/starch blend films derived from natural sources: incorporating thiourea and urea coupling agents with stearic acid plasticizer. [PDF]
Badr MM +5 more
europepmc +1 more source

