Results 151 to 160 of about 2,750 (210)

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

open access: yesAdvanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song   +5 more
wiley   +1 more source

Reimagining Lignin Valorization: Synthetic Biology–Enabled Sustainable Aromatic Carbon Biomanufacturing

open access: yesAdvanced Science, EarlyView.
The diagram illustrates a sustainable model of lignin valorization and carbon cycling based on microbial cell factories. Using lignin as the feedstock, synthetic biology technologies, including depolymerization, cell factory construction, pathway gene module integration, and metabolic network regulation, are applied to convert lignin into bulk ...
Na Li   +4 more
wiley   +1 more source

Programmable Encapsulation Enables On‐Demand Proliferation of Therapeutic Bacteria for Potent Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A programmable encapsulation technology is developed to reduce bacterial immunogenicity and proliferation after systemic administration. The cross‐linked polymer networks around individual bacteria enable immunogenic shielding and permit selective proliferation in tumors, allowing the bacteria to convert tumor‐accumulated ammonia into L‐arginine and ...
Jianhui Yang   +12 more
wiley   +1 more source

Ultrasound‐Activated Piezoelectric Neuroimmune Hydrogel Orchestrates Neurogenesis‐Macrophage Crosstalk in Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Kai Wang   +13 more
wiley   +1 more source

Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan   +14 more
wiley   +1 more source

Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States

open access: yesAdvanced Science, EarlyView.
Manipulation of intranuclear divalent cation concentrations rapidly and reversibly remodels chromatin packing domains in living cells. Magnesium depletion disrupts domain compaction, heterochromatin organization, and transcriptional regulation, whereas magnesium loading promotes more compact and stable domains.
Cody L. Dunton   +13 more
wiley   +1 more source

An Introduction of Biodegradable Polymers, Modes of Biodegradation and Designing of Biodegradable Polymers

Research Journal of Pharmacy and Technology, 2017
Biodegradable polymers are a newly emerging field. Biodegradable polymers are useful for various applications in medical, agriculture, drug release and packaging fields. Biodegradable polymers have received much more attention in the last decades due their potential applications in the fields related to environmental protection and the maintenance of ...
Rajeev Kumar   +2 more
openaire   +1 more source

Biodegradable Polymers

2021
This book is about development of biodegradable polymers alternatives, which are required to save our reserves of fossil fuels and to save our mother earth from further environmental degradation. This book deals with the family of biodegradable polymers which have to be prepared with a novel idea of studying polymers with a “Cradle to Grave” approach ...
Sayan Deb Dutta, Ki-Taek Lim
openaire   +2 more sources

Biodegradable polymer scaffolds

Journal of Materials Chemistry B, 2016
Tissue engineering aims to repair the damaged tissue by transplantation of cells or introducing bioactive factors in a biocompatible scaffold.
Shan-Hui, Hsu   +2 more
openaire   +2 more sources

Biodegradable polymers as biomaterials

Journal of Biomaterials Science, Polymer Edition, 1995
Biomaterials are used in prostheses and medical devices for different purposes. Polymers are the most diverse class of biomaterials. All biomaterials must meet certain criteria and regulatory requirements before they can be qualified for use in medical applications. Biocompatibility is one of the most important requirements. Both nondegradable polymers
openaire   +2 more sources

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