Results 61 to 70 of about 2,192 (164)

Obstructive Sleep Apnea and BMI, Body Fat Percentage in the East Asian Population: A Bidirectional and Multivariate Mendelian Randomization Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To explore the causal relationship between obstructive sleep apnea and body fat percentage and body mass index (BMI) in the East Asian population by using bidirectional Mendelian randomization and multivariate Mendelian randomization.
Rui Fan, Wen‐Jun Lu, Hua Zhang, Hai‐Ling Jiang, Tao Li, Yan Yan   +5 more
wiley   +1 more source

Rosemary metabolite carnosic acid opens Kv1.1 via its voltage sensor and corrects Kv1.1‐linked episodic ataxia in mice

British Journal of Pharmacology, EarlyView.
Background and Purpose Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder caused primarily by loss‐of‐function mutations in the voltage‐gated potassium channel Kv1.1 (KCNA1). Small molecules that restore Kv1.1 activity hold promise as targeted therapies for EA1, yet current pharmacological strategies remain limited ...
Rían W. Manville, Ryan F. Yoshimura, Hanh A. Nguyen, Ruiming Zhao, Derk J. Hogenkamp, Steve A. N. Goldstein, Geoffrey W. Abbott   +6 more
wiley   +1 more source

Disentangling the effect of brain insulin resistance on brain health (BIR‐BrainHealth): Rationale and study protocol

Diabetic Medicine, EarlyView.
Abstract Aims Insulin signalling in the brain is crucial for systemic metabolic regulation and cognitive function. In some individuals, these effects are reduced, a phenomenon referred to as brain insulin resistance (BIR). This condition may contribute to the elevated risk of cognitive decline and dementia in diabetes, yet its prevalence, mechanisms ...
Sabrina Wangler, Peter Sørensen, Konni Kass, Nicole Jaqueline Jensen, Mark Bitsch Vestergaard, Julia Hummel, Ronja Völk, Julie Christine Antvorskov, Flemming Pociot, Jørgen Rungby, Martin Heni, Henrik Bo Wiberg Larsson   +11 more
wiley   +1 more source

Clinical characteristics of Sarcopenic obesity in Japanese people with type 2 diabetes: A post hoc analysis of the sub‐cohort iDIAMOND study

Journal of Diabetes Investigation, EarlyView.
Among participants aged 40–75 years, sarcopenic obesity was observed in 4.9% of those with T2D and 0.5% of non‐D individuals. Sarcopenic obesity is more prevalent in individuals with T2D and is associated with impaired physical QOL, reduced walking ability, and increased falls.
Hiroyasu Mori, Kasei Ko, Satoko Notomi, Sumiko Yoshida, Tetsuyuki Yasuda, Yutaka Umayahara, Sayoko Shimizu, Kayoko Ryomoto, Kazutomi Yoshiuchi, Saeko Osawa, Tsunehiko Yamamoto, Akio Kuroda, Munehide Matsuhisa   +12 more
wiley   +1 more source

Shark preferences: Only subtle effects of electromagnetic field exposure and substrate type on small‐spotted catshark (Scyliorhinus canicula) behaviour

Journal of Fish Biology, EarlyView.
Abstract Offshore wind energy plays a crucial role in the transition to low‐carbon power generation. The expansion of offshore wind farms (OWFs) introduces anthropogenic electromagnetic fields (EMFs) from subsea power cables. Elasmobranchs, including sharks and rays, are sensitive to natural electric and magnetic fields used for navigation and prey ...
Lotte J. Bouwman, Annemiek Hermans, Jeroen Hubert, Reindert Nijland, Henrice Jansen, Jildou Schotanus, Hendrik V. Winter   +6 more
wiley   +1 more source

Evaluating School‐Based Obesity Prevention Interventions in 6‐ to 12‐Year‐Old Children: A Scoping Review of All Reported Outcomes and Expert Consultation

Obesity Reviews, EarlyView.
ABSTRACT Introduction This scoping review aims to identify all outcomes reported in school‐based obesity prevention interventions in childhood. It serves as an essential first step towards developing an internationally agreed‐upon Core Outcome Set (COS), which defines what should be measured in all school‐based childhood obesity prevention studies ...
Teatske M. Altenburg, Lotte W. de Vries, Iris J. Grooten, Janneke van 't Hooft, Arend W. van Deutekom, Tessa Roseboom, Erica van den Akker, Michael Duncan, Ulf Ekelund, John J. Reilly, Lisa Reilly, Annette Stafleu, Martyn Standage, Mai J. M. Chinapaw, Deirdre M. Harrington   +14 more
wiley   +1 more source

Maternal Overnutrition in Pregnancy Predicts Greater Body Mass Index Gains in Offspring by Early Midlife: A Systematic Review and Meta‐Analysis

Obesity Reviews, EarlyView.
ABSTRACT Maternal overnutrition during pregnancy predisposes children to increased adiposity later in life. This systematic review and meta‐analysis examined how this association persists into adulthood and whether it differs by sex. MEDLINE, EMBASE, Scopus, and CENTRAL were searched for human studies published in English before May 2025.
Szimonetta Eitmann, Péter Mátrai, Péter Hegyi, Márta Balaskó, Erika Pétervári   +4 more
wiley   +1 more source

Cognitive Symbionts. Expanding the Scope of Cognitive Science With Fungi

Topics in Cognitive Science, EarlyView.
Abstract It has been argued that fungi have cognitive capacities, and even conscious experiences. While these arguments risk ushering in unproductive disputes about how words like “mind,” “cognitive,” “sentient,” and “conscious” should be used, paying close attention to key properties of fungal life can also be uncontroversially productive for ...
Matteo Colombo
wiley   +1 more source

The effects of bed rest on cardiometabolic health: A systematic review and meta‐analysis

Experimental Physiology, EarlyView.
Abstract Horizontal bed rest (HBR) and head‐down tilt (HDT) are models of physical inactivity. In this systematic review and meta‐analysis, we aimed to quantify changes in cardiometabolic outcomes during HBR and HDT in healthy adults. Following the PRISMA guidelines, we searched PubMed, Scopus, Web of Science and Cochrane Library until 1 October 2025 ...
Konstantinos Prokopidis, Tyler Daubrah‐Scott, Alyssa Varanoske, Jordi Morwani‐Mangnani, David D. Church, Colleen S. Deane, Bethan E. Phillips, Emily J. Arentson‐Lantz   +7 more
wiley   +1 more source

Metabolic pattern across energy imbalance: An exploratory metabolomics study of female body weight extremes including anorexia nervosa and athletes

Experimental Physiology, EarlyView.
Abstract In anorexia nervosa (AN), prolonged metabolic adaptation to severe energy deficiency can impair treatment efficacy. Similarly, low energy availability poses a recognized risk to athletes, potentially compromising health and performance. This cross‐sectional study aimed to characterize the plasma metabolic pattern of females with varying ...
Sonja Lackner, Olli Kärkkäinen, Sabrina Mörkl, Wolfram Müller, Alfred Fürhapter‐Rieger, Kati Hanhineva, Sandra Johanna Holasek   +6 more
wiley   +1 more source