Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Correction: Ali et al. Real-Time Recognition of NZ Sign Language Alphabets by Optimal Use of Machine Learning. <i>Bioengineering</i> 2025, <i>12</i>, 1068. [PDF]
Ali M, Hosseini SE, Pervez S, Ahmad M.
europepmc +1 more source
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Correction: Hoang, P.; Guccione, J. Finite Element Modeling in Left Ventricular Cardiac Biomechanics: From Computational Tool to Clinical Practice. <i>Bioengineering</i> 2025, <i>12</i>, 913. [PDF]
Hoang P, Guccione J.
europepmc +1 more source
Bioengineering: Genetic Logic Gates Enable Patterning of Amyloid Nanofibers (Adv. Mater. 39/2019) [PDF]
Ebuzer Kalyoncu +3 more
openalex +1 more source
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
Correction: Zhu et al. Injectable and Assembled Calcium Sulfate/Magnesium Silicate 3D Scaffold Promotes Bone Repair by In Situ Osteoinduction. <i>Bioengineering</i> 2025, <i>12</i>, 599. [PDF]
Zhu W +8 more
europepmc +1 more source
SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source

