Results 191 to 200 of about 376,139 (290)
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran+5 more
wiley +1 more source
Government and Society: New bioengineering institute at the NIH
Paul D. Thacker
openalex +1 more source
Sustained phenotypic correction of hemophilia a mice following oncoretroviral-mediated expression of a bioengineered human factor VIII gene in long-term hematopoietic repopulating cells [PDF]
Morvarid Moayeri+4 more
openalex +1 more source
Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez+3 more
wiley +1 more source
A Multi-Stage Framework for Kawasaki Disease Prediction Using Clustering-Based Undersampling and Synthetic Data Augmentation: Cross-Institutional Validation with Dual-Center Clinical Data in Taiwan. [PDF]
Huang HC+5 more
europepmc +1 more source
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso+5 more
wiley +1 more source
Does Malpositioning of Pedicle Screws Affect Biomechanical Stability in a Novel Quasistatic Test Setup? [PDF]
Schleifenbaum S+5 more
europepmc +1 more source
BIOENGINEERED CONTRACTILE CONSTRUCTS FROM MYOSIN AND ACTOMYOSIN MULTILAYERS
Baier Re, Carsten Zobel
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The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali+5 more
wiley +1 more source