Results 181 to 190 of about 32,756 (214)

Individual Bioequivalence Revisited

Clinical Pharmacokinetics, 2001
For decades, the establishment of bioequivalence has generally relied on the comparison of population averages between the test and reference formulations. In the early 1990s, individual bioequivalence was proposed to ensure that an individual could be switched from the reference product to the test product with unchanged efficacy and safety.
M L, Chen, L J, Lesko
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Stereochemistry and Bioequivalence

The Journal of Clinical Pharmacology, 1992
Despite the fact that many important drugs are chiral, for a variety of reasons they are marketed as racemates (i.e., an equal proportion of two enantiomers). Although enantiomers of racemic drugs often differ from one another in their pharmacodynamic and pharmacokinetic properties, bioequivalence assessments are made using nonstereospecific assays ...
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Bridging Bioequivalence Studies

Journal of Biopharmaceutical Statistics, 2004
In some new regions, an innovative drug of the original region was not marketed. However, after the patent of the innovative drug is expired, a generic copy of the innovative drug from the original region was introduced and approved for marketing in the new region.
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On Testing for Bioequivalence

Biometrics, 1984
A number of methods have been proposed for statistical analysis of bioequivalence trials. A new method is proposed and compared to three previously suggested techniques. This comparison clarifies the relationship among the four methods and yields practical suggestions regarding statistical tests.
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Thyroxine Bioequivalency

Annals of Internal Medicine, 1985
BARRY A. WARNER, RICARDO DEGUZMAN
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Bioequivalence

2021
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Statistical issues in bioequivalence [correction of bioequivalance].

Statistics in medicine, 2001
There has been much work recently on individual bioequivalence and the topic has attracted considerable controversy. Some previous controversies regarding average bioequivalence are examined. It is argued that a contributory factor in these controversies may have been confusion over the purpose of bioequivalence trials.
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Bioequivalence and Interchangeability

Journal of Pharmaceutical Sciences, 1978
S, Hwang, P B, Huber, M, Hesney, K C, Kwan   +3 more
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Bioequivalence and Pharmacogenetics

Current Pharmacogenomics and Personalized Medicine, 2014
DEMİRPOLAT, Eren, AYCAN, Mükerrem Betül   +1 more
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Bioequivalence

2011
Graham Lockwood, Robert Kringle
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