Results 281 to 290 of about 205,778 (362)

Fatty‐acid amide hydrolase inhibition mitigates Alzheimer's disease progression in mouse models of amyloidosis

The FEBS Journal, EarlyView.
Enhancing endocannabinoid signaling by targeting FAAH effectively mitigates cognitive deficits, reduces amyloid pathology, and modulates neuroinflammatory responses in a preclinical model of Alzheimer's disease. This effect is potentially mediated by attenuating the Aβ‐induced overexpression of the Bace1 gene through CB1‐dependent hypermethylation of ...
Sergio Oddi, Lucia Scipioni, Antonio Totaro, Giacomo Giacovazzo, Francesca Ciaramellano, Daniel Tortolani, Alessandro Leuti, Rita Businaro, Federica Armeli, Andras Bilkei‐Gorzo, Roberto Coccurello, Andreas Zimmer, Mauro Maccarrone   +12 more
wiley   +1 more source

Biotechnology, bioethics and the poor

, 2001
Minakshi Bhardwaj
openalex   +1 more source

Mammalian TatD DNase domain containing 1 (TATDN1) is a proteostasis‐responsive gene with roles in ventricular structure and neuromuscular function

The FEBS Journal, EarlyView.
Twin‐arginine translocation D (TatD) homologs are found across all kingdoms, with debated roles in DNA degradation and protein quality control in unicellular organisms. We characterize TATDN1, the mammalian TatD orthologue, as a proteostatic stress‐responsive cytosolic protein dispensable for DNA degradation.
Gisel Barés, Aida Beà, Anna Sancho‐Balsells, Juan G Valero, David Aluja, Javier Inserte, Sandra García‐Carpi, Elisabet Miró‐Casas, Sara Borràs‐Pernas, Sara Hernández, Ana Martínez‐Val, Jesper V Olsen, Francesc Tebar, Xavier Cañas, Joan X. Comella, Patricia Pérez‐Galán, Marisol Ruiz‐Meana, Albert Giralt, Marta Llovera, Daniel Sanchis   +19 more
wiley   +1 more source

Correction: Developing Disability-Focused Pre-Health and Health Professions Curricula. [PDF]

J Med Humanit
Bracken RC, Richman KA, Garden R, Fischbein R, Bhambra R, Ragina N, Dawson S, Cascio A.   +7 more
europepmc   +1 more source

Human tissue kallikrein 14 induces the expression of IL‐6, IL‐8, and CXCL1 in skin fibroblasts through protease‐activated receptor 1 signaling

The FEBS Journal, EarlyView.
Human tissue kallikrein 14 (KLK14), a skin protease, may mediate paracrine signaling in wound healing. KLK14 released by epithelial cells activates fibroblasts via PAR‐1 activation, inducing IL‐6, IL‐8, and CXCL1 expression. These cytokines in turn promote keratinocyte proliferation and migration, resulting in wound closure.
Laura Sasiadek, Ewa Bielecka, Katherine Falkowski, Magdalena Kulczycka, Grzegorz Bereta, Anna Maksylewicz, Natalia Zubrzycka, Ewelina Dobosz, Joanna Kozieł, Justyna Drukała, Maciej Lech, Natalia Horbach, Marcin Poręba, Klaudia Brix, Grzegorz Dubin, Jan Potempa, Tomasz Kantyka   +16 more
wiley   +1 more source

Correction: Mota-Rojas et al. Controversial Topics in Animal Welfare in Latin America: A Focus on the Legislation Surrounding the Human-Companion Animal Relationship and Animals Used for Recreational Practices. <i>Animals</i> 2023, <i>13,</i> 1463. [PDF]

Animals (Basel)
Mota-Rojas D, Strappini A, Whittaker AL, Ghezzi M, Titto CG, Calderón-Maldonado N, Mora-Medina P, Domínguez-Oliva A, Gómez-Prado J, Hernández-Ávalos I, José-Pérez N, Casas-Alvarado A, Orihuela A.   +12 more
europepmc   +1 more source

Perceptions of Visiting Oral Health Service Providers: Using the Q Method and Focusing on Suggestions for the Role of Dental Hygienists in a Community

Gerodontology, EarlyView.
ABSTRACT Objective This study aimed to identify the types and characteristics of providers' (dental hygienists and caregivers) perceptions of visiting oral health care services and explore the contents of visiting oral health care services and the social role of dental hygienists in promoting the health of older adults in the upcoming post‐aged society.
Sue‐Hyang Lee, Soo‐Myoung Bae, Bo‐Mi Shin, Sun‐Jung Shin   +3 more
wiley   +1 more source

Confucian reflections on the new reproductive model of ROPA. [PDF]

Bioethics
Ma Y, Chen H, Muyskens K.
europepmc   +1 more source

Bodily Autonomy, Reproductive Rights and Company‐Sponsored Fertility Benefits: A Call to Action

Gender, Work &Organization, EarlyView.
ABSTRACT This commentary considers company‐sponsored fertility benefits (CSFBs) and their use by organizations. We highlight the lack of attention to these benefits in the gender and management literature. Indeed, despite the importance of the topic very few gender researchers, and even fewer management scholars have deemed the erosion of female ...
Cliodhna Mackenzie, Elaine O'Brien, Thomas Garavan   +2 more
wiley   +1 more source

Authors meet critics: What is a person? Untapped insights from Africa. [PDF]

J Med Ethics
Jecker NS, Atuire CA.
europepmc   +1 more source