IL-33 Elicits LTC<sub>4</sub> Synthesis in Allergic Inflammation via ST2-Mediated Activation of Eosinophils. [PDF]
Eur J ImmunolAllergic reaction‐derived IL‐33 activates ST2 to trigger selective eosinophil activation. IL‐33 in a type 2 immune response environment induces biogenesis of lipid bodies in eosinophils, platforms for the generation of lipid mediators, and selectively triggers LTC4 production.
Rosário-Garcia VF +11 more
europepmc +2 more sources
In Vivo and Ex Vivo Evaluation of 1,3-Thiazolidine-2,4-Dione Derivatives as Euglycemic Agents
PPAR Research, 2021 Thiazolidinediones (TZDs), used to treat type 2 diabetes mellitus, act as full agonists of the peroxisome proliferator-activated receptor gamma. Unfortunately, they produce adverse effects, including weight gain, hepatic toxicity, and heart failure.
Diana Alemán-González-Duhart +4 more
doaj +1 more source
Journal of Fungi, 2023 Cryptococcosis is a systemic mycosis affecting immunosuppressed individuals, caused by various Cryptococcus species. The current treatment utilizes a combination of antifungal drugs, but issues such as nephrotoxicity, restricted or limited availability ...
Vinicius Alves +7 more
doaj +1 more source
The Spacing Effect for Structural Synaptic Plasticity Provides Specificity and Precision in Plastic Changes [PDF]
, 2017 In contrast to trials of training without intervals (massed training), training trials spaced over time (spaced training) induce a more persistent memory identified as long-term memory (LTM).
Gelb, Bruce +3 more
core +1 more source
SUSCETIBILIDADE BIOFÍSICA A SECAS DA SUB-BACIA HIDROGRÁFICA DO RIO PIRACURUCA (CE-PI)
Boletim Goiano de Geografia, 2020 O estudo teve como objetivo realizar caracterização biofísica da Sub-bacia Hidrográfica do rio Piracuruca (CE-PI), como princípio para realização de diagnóstico, e análise da suscetibilidade biofísica às secas da Sub-bacia em questão. Para tal finalidade
Francílio de Amorim dos Santos +2 more
doaj +1 more source
Serotonin 2a Receptor and Serotonin 1a Receptor Interact Within the Medial Prefrontal Cortex During Recognition Memory in Mice [PDF]
, 2015 Episodic memory, can be defined as the memory for unique events. The serotonergic system one of the main neuromodulatory systems in the brain appears to play a role in it.
Gaël eMalleret +6 more
core +2 more sources
Early Cognitive/Social Deficits and Late Motor Phenotype in Conditional Wild-Type TDP-43 Transgenic Mice [PDF]
, 2016 Frontotemporal Dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two neurodegenerative diseases associated to mislocalization and aggregation of TAR DNA-binding protein 43 (TDP-43).
Alfieri, Julio Armando +2 more
core +2 more sources
Odontoestomatología, 2022 Introducción:La hiperglicemia inhibe la neoformación ósea, potencia la reabsorción y altera la oseointegración(1). Numerosos reportes muestran que la hiperglicemia induce estrés oxidativo celular, se producen especies oxidantes y radicales libres que ...
MARIA CARMEN SUÁREZ AROCENA +2 more
doaj +3 more sources
5-HT2a receptor in mPFC influences context-guided reconsolidation of object memory in perirhinal cortex [PDF]
, 2018 Context-dependent memories may guide adaptive behavior relaying in previous experience while updating stored information through reconsolidation. Retrieval can be triggered by partial and shared cues.
Bekinschtein, Pedro Alejandro +5 more
core +1 more source
De la Cristalografía a la biología estructural, un siglo de descubrimientos
Arbor: Ciencia, Pensamiento y Cultura, 2015 La cristalografía, la técnica más ampliamente usada para estudiar la estructura de la materia, ha evolucionado en las ciencias de la vida hacia la biología estructural, una exitosa área de investigación encaminada a comprender el funcionamiento de los ...
Guillermo Montoya
doaj +1 more source