Results 121 to 130 of about 8,562 (245)

Development of Pancreatic Construct for Type 1 Diabetes by 3D cell Printing Technology

open access: yes, 2022
1
Dong-Woo Cho   +8 more
core  

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best   +5 more
wiley   +1 more source

Supramolecular Engineering of Fluid Pressure in Filamentous Hybrid Double Network Hydrogels for 3D Chondrocyte Culture

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.
Inspired by the water‐rich and interconnected biopolymer networks of native load‐bearing tissues, we disclose a connectable design for a hybrid filamentous supramolecular and covalent double network hydrogel generated through in situ photopolymerization.
Ciqing Tong   +11 more
wiley   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong   +4 more
wiley   +1 more source

Stackable 3D-printed core-shell nozzle system for multi-shell fiber and microdroplet generation

open access: yesMaterials & Design
Microfluidics is increasingly utilized in biofabrication to create more complex fiber and droplet structures, including those that involve multiple materials.
Jianfeng Li, Peer Fischer
doaj   +1 more source

Biofabrication platforms

open access: yes
This PhD thesis investigates the possibility to manufacture advanced models for the study of chronic kidney disease (CKD), by means of bioprinting. One of the endpoints of CKD is kidney fibrosis, which is characterized by cells secreting an excessive amount of proteins, limiting the kidney functionality.
openaire   +2 more sources

Synchronizing the Osteochondral Regeneration Process through Spatial Patterning of Stable and Hypertrophic Cartilage Organoids

open access: yesAdvanced Materials, Volume 38, Issue 33, 12 June 2026.
Zonated osteochondral assembloid implants are engineered through scaffold‐free spatial assembly of induced pluripotent stem cell (iPSC)‐derived chondrocyte organoids and periosteum‐derived osteogenic organoids. Implanted into full‐thickness rat osteochondral defects, they promote hyaline‐like cartilage repair, support subchondral bone formation with ...
Liuqi Peng   +3 more
wiley   +1 more source

Thiolated Polymers in 3D Bioprinting: Control of Gelation

open access: yesAdvanced Materials, Volume 38, Issue 35, 23 June 2026.
Thiolated polymers are established as programmable bioinks for 3D bioprinting, integrating versatile crosslinking chemistries with redox‐responsive control. This work demonstrates how molecular design and external triggers define gelation kinetics, printability windows, and structural fidelity, enabling stable, high‐resolution constructs and advancing ...
Soheil Haddadzadegan   +2 more
wiley   +1 more source

Multimaterial Triphasic Scaffold Replicates Enthesis Microenvironment to Modulate Early Cell Responses

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 6, June 2026.
A bioinspired triphasic scaffold integrating 3D printed polycaprolactone and electrospun poly(lactic‐co‐glycolic acid) is developed to replicate the organization of the tendon‐to‐bone enthesis. Cyclic mechanical stimulation induces spatially defined cell morphology and lineage‐related gene expression in human mesenchymal stem cells, highlighting the ...
Ginevra Pegollo   +7 more
wiley   +1 more source

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