A dual-host regulatory hub integrating biofilm formation and innate immunity resistance. [PDF]
Baillez A +13 more
europepmc +1 more source
Porphyrin‐Based Porous Materials for Antibacterial Applications
Porphyrin‐based porous materials have excellent photophysical properties and tunable structures for high‐efficiency antibacterial therapy. This review comprehensively discusses the structural design strategies and synthetic pathways of the four main types of porphyrin‐based porous materials, summarizes their cross‐domain antimicrobial applications, and
Xiao‐Xue Liang +4 more
wiley +1 more source
Spatiotemporal Regulation of Hierarchical Assembly of Hydroxyapatite for Enamel Remineralization
Biomimetic repair exhibits unique advantages for enamel regeneration compared with conventional clinical treatments. An enzymatic mineralization system (EMS) is developed, where the resulting HAP nanorods hierarchically assemble into a highly ordered structure on the enamel surface through the spatiotemporal modulation of interfacial energies of ...
Zhenhang Tang +15 more
wiley +1 more source
Disruption of quorum sensing and biofilm formation by lawsone in gram-negative bacteria. [PDF]
Anwer R.
europepmc +1 more source
Porcupine‐Quill‐Inspired Shape‐Morphing Biointerfaces Disassemble Biofilms
A porcupine‐spine‐inspired dynamic offensive bio‐interface is developed for active biofilm disassembly. By coupling electrically driven nano‐dagger penetration with light‐triggered ROS generation, the surface overcomes the passive limitations of conventional mechano‐bactericidal topographies, achieving near‐complete biofilm eradication, strong ...
Feng Qian +10 more
wiley +1 more source
Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont
Noncanonical biochemistry of the peloruside PKS characterized in this work, comprising double bond generation by a noncanonical tridomain (blue), acetyl‐CoA recycling (orange), and proofreading systems (purple and yellow). The Z‐double bond is installed by TEB1 through O‐acetylation and acetate elimination. The acyl ligase PelB (AL, orange) selectively
Amy E. Fraley +11 more
wiley +2 more sources
AI‐based tools enable rapid characterization of bacterial ultrastructure in low‐dose cryogenic transmission electron microscopy. The envelope thickness tool quantifies membrane thickness and anisotropy. The flagella module analyzes filament morphology and detects cell‐flagella contacts.
Sita Sirisha Madugula +10 more
wiley +1 more source
Biofilm formation during pneumococcal carriage imprints naturally acquired humoral immunity. [PDF]
Lane JR +12 more
europepmc +1 more source
Dynamic Obstacle Avoidance of Metamorphic Microrobots Using Concentric Sector Navigator
Metamorphic magnetic microrobots are navigated using a concentric sector navigator for dynamic obstacle avoidance in both microroller and swarm states. After microroller transport, citrate‐triggered dissolution releases nanoparticles that reassemble into a controllable swarm.
Zhaowen Su +4 more
wiley +1 more source
Supramolecular Assembly of an Antimicrobial Peptide Into a Pore
Supramolecular assembly of an AMP is linked to transport across the Staphylococcus aureus membrane. ABSTRACT Antimicrobial peptides (AMPs) have long been ascribed the ability to form pores. These structures, some observed, others inferred, vary in their mechanisms of action, though most are associated with lysis.
Kathyana Deeyagahage +3 more
wiley +2 more sources

