Results 141 to 150 of about 206,560 (313)

Investigation into the formation and susceptibility of Candida albicans biofilms and denture plaque in vitro.

, 2005
Microbial biofilms are wide-spread in nature and the organisms within them are often able to cause acute and chronic human diseases. The nature of biofilms is complex and the organisms behave differently from their planktonic counterparts.
Lamfon, H.
core  

Is Increased Biofilm Formation Associated with Decreased Antimicrobial Susceptibility? A Systematic Literature Review

Biofilm formation is a key factor in microbial survival and persistence, often contributing to reduced antimicrobial susceptibility. This systematic literature review investigates whether increased biofilm formation correlates with decreased antibiotic ...
Tom Coenye, Lobke Vanommeslaeghe, Abhinav Madduri   +2 more
core   +1 more source

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

Advanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng, Lianqi Liu, Chenghua Liu, Fei Xie, Jingwen Dong, Xiaoyu Qin, Shunxiang Huang, Xian Li, Xingyuan Kou, Hongbin Deng, Jiannan Feng, Wu Zhong, Dian Xiao, Xinbo Zhou   +13 more
wiley   +1 more source

Comparative analysis of the influence of BpfA and BpfG on biofilm development and current density in Shewanella oneidensis under oxic, fumarate- and anode-respiring conditions

Scientific Reports
Biofilm formation by Shewanella oneidensis has been extensively studied under oxic conditions; however, relatively little is known about biofilm formation under anoxic conditions and how biofilm architecture and composition can positively influence ...
Edina Marlen Klein, Hannah Heintz, René Wurst, Simon Schuldt, Hendrik Hähl, Karin Jacobs, Johannes Gescher   +6 more
doaj   +1 more source

Effect of Media and pH on Biofilm Formation in High and Low Biofilm-forming Isolates from Chronic Diabetic Foot Ulcers

Journal of the Scientific Society
Introduction: Biofilm formation among clinical isolates poses a significant challenge, especially in chronic wounds such as chronic diabetic foot ulcers (CDFUs).
MasoodAhmed Tahashildar, Sheetal Harakuni, Shrishail Metgud, Basavaraj M. Kajagar, Manoj Togale   +4 more
doaj   +1 more source

Dual‐Stage Microneedle Patch With Lipid Droplet‐Mediated ‘Capture‐Kill’ and Sustained Release for Enhanced Wound Healing

Advanced Science, EarlyView.
We report a lipid‐droplet‐engineered, gallium‐loaded sonodynamic therapeutic platform (LDTG) incorporated into a bilayer microneedle (MN) patch co‐delivering all‐trans retinoic acid (ATRA), termed LDTG A‐MNs, for synergistic antibacterial therapy and accelerated wound repair.
Peng Jiang, Meijun Jiang, Jiapeng Lei, Wen Zhang, Huiyuan Yang, Xueyang Wang, Siyu Zhang, Qiongfang Ruan, Shuhua Liu, Wei Li   +9 more
wiley   +1 more source

Surface fouling by Candida albicans on steel modified with various surface-assembled monolayers

The Microbe
Fungal biofilms are a growing issue in human health and disease, increasing patient morbidity, while causing a large economic burden for treatment of biofilm derived infections.
Brian De La Franier, Michael Thompson
doaj   +1 more source

Mutability and survival of pseudomonas aeruginosa in multi-species drinking water biofilm communities

, 2012
Pseudomonas aeruginosa is an important opportunistic pathogen of humans and also has the ability to form biofilms in drinking water. However, the survival, persistence and the control of this pathogen within mixed-species bacterial communities in ...
Kennedy, Enyioha
core  

H2S‐Amplified “Three‐in‐One” Antibacterial Strategy for Periodontitis Treatment Using a Photosensitive Pillararene‐Embedded COF/MOF Hybrid

Advanced Science, EarlyView.
The integration of ROS‐generating systems with H2S depletion strategies effectively overcomes the limitations imposed by endogenous antioxidant defenses on ROS‐based antimicrobial therapies. In this study, the Cu‐MOF is incorporated into pillararene‐embedded COF, achieving a “three‐in‐one” antimicrobial effect that markedly alleviated periodontal ...
Shuang Liang, Meng‐Hao Li, Liang Cheng, Tian‐Shou Zhang, Hui Hui, Yan Wang, Hong‐Pu Zhang, Bo‐Wen Liu, Lin Wang, Ying‐Wei Yang   +9 more
wiley   +1 more source