Results 201 to 210 of about 206,560 (313)

Tobramycin pharmacokinetic and pharmacodynamic targets in people with cystic fibrosis

British Journal of Clinical Pharmacology, EarlyView.
Intravenous tobramycin is a first‐line treatment for Pseudomonas aeruginosa infection in people with cystic fibrosis (CF). Tobramycin exhibits concentration‐dependent activity; however, excess drug exposure can lead to nephrotoxicity and ototoxicity. While dosing typically targets serum peak (Cmax) and trough (Cmin) concentrations, the area under the ...
Kiera H. Harwood, Sarah Bannister, Stephen Duffull, April Martinez, Sarath Ranganathan, Shivanthan Shanthikumar, Amanda Gwee   +6 more
wiley   +1 more source

Biofilm formation directly correlates with cell viability in Candida tropicalis on polypropylene. [PDF]

Appl Microbiol Biotechnol
Yogendraiah KM, Sadanandan B, Natraj LK, Vijayalakshmi V, Shetty K.   +4 more
europepmc   +1 more source

Numerical and Experimental Assessment of Oxygen Distribution in a Perfusion Bioreactor to Mimic the Osteochondral Niche

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Oxygen supply is a critical parameter in 3D cell cultivation using bioreactors. Since bioreactor designs often prioritise practical constraints, understanding the oxygen supply dynamics of the media is crucial for achieving either uniform or spatially controlled oxygen delivery.
Franziska Alt, Eric Langner, Hans‐Peter Wiesmann, Thomas Wallmersperger, Benjamin Kruppke   +4 more
wiley   +1 more source

Retrieving of diguanylate cyclases responsible for biofilm formation and antibiotic resistance in Acinetobacter baumannii. [PDF]

BMC Microbiol
Li B, Zou L, Liu X.
europepmc   +1 more source

Real‐Time Biomass Estimation in High‐Density Yeast Fermentations Using Soft Sensor Modeling

Biotechnology and Bioengineering, EarlyView.
Accurate biomass measurements, both offline and online, are essential to improve prediction and control in yeast fermentation. This study develops regression‐based predictive models to correlate offline measurements (Dry Cell Weight and OD600 from a spectrophotometer) with online OD860 probe signals to provide accurate real‐time biomass estimations and
Ana G. Del Hierro, José Luis Checa‐Barrera, Juan A. Moreno‐Cid, Eoin Casey   +3 more
wiley   +1 more source

Acrylic-based occlusal device materials - the influence of manufacturing techniques on material properties and the propensity for biofilm formation. [PDF]

Biomater Investig Dent
Haugli KH, Samuelsen JT, Aas V, Dragland IS, Charnock C.   +4 more
europepmc   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Bacterial factors required for biofilm formation in <i>Staphylococcus epidermidis</i> are linked to contact activation. [PDF]

Front Cell Infect Microbiol
Rademacher A, Ekat K, Skusa R, Scharnagl L, Knipp F, Warnke C, Marcinek J, Tobien S, Frank M, Khaimov V, Rohde H, Kreikemeyer B, Oehmcke-Hecht S.   +12 more
europepmc   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Factors Influencing Biofilm Formation of <i>Salmonella</i> spp. and the Biofilm-Degrading Potential of Essential Oils. [PDF]

Foods
Seres-Steinbach A, Szabó P, Balázs Lilla V, Riethmüller E, Szmolka A, Bányai K, Schneider G.   +6 more
europepmc   +1 more source