Results 111 to 120 of about 1,259,171 (302)

Limits to growth and what keeps a biofilm finite

open access: yes, 1999
Two of the factors, shear erosion and diffusive mass transfer, which limit the growth of heterogeneous biofilms are considered. For permeable beds of particulates, with a regulated throughflow, equating shear induced erosion and biofilm growth, leads to ...
Dodds, Ian   +3 more
core   +1 more source

5-Fluorouracil Inhibits Bacterial Growth and Reduces Biofilm in Addition to Having Synergetic Effects with Gentamicin Against Pseudomonas aeruginosa

open access: yes
Pseudomonas aeruginosa is a multidrug-resistant pathogen known for chronic infections, mainly due to biofilm formation. This study aimed to explore the potential repurposing of 5-fluorouracil (5-FU), an anticancer drug, to treat P. aeruginosa infections.
May M. Alrashed   +3 more
core   +1 more source

Mesoporous PU/PEDOT:PSS Electrodes Reveal Population‐Level Stochastic Bioelectrical Dynamics in Marine Diatoms

open access: yesAdvanced Science, EarlyView.
Mesoporous mixed ionic‐electronic PU/PEDOT: PSS electrodes enable label‐free detection of stochastic extracellular bioelectrical dynamics in living Phaeodactylum tricornutum. Living diatoms actively modulate interfacial ionic dynamics, establishing stochastic electrochemical noise as a sensitive probe of microbial bioelectrochemical activity and a new ...
David M. S. Silva   +7 more
wiley   +1 more source

INHIBITION OF DIFFERENT STAGES OF BIOFILM OF PSEUDOMONAS AERUGINOSA PA01 BY ISOLATED BACTERIOPHAGE P2 [PDF]

open access: yes, 2015
 Biofilm mediated protection of pathogens from environmental stresses are recognized as one of the major threat worldwide, which encourage theresearcher to search for other alternative approach. Bacteriophage therapy is one such effective and controlled
Kaistha, Shilpa   +2 more
core   +1 more source

Reversing Macrophage Immunometabolic Dysfunction in Prolonged Infections Via a Glutaminolysis‐Fueled Restoration‐Based Hierarchically Selective Therapeutic System

open access: yesAdvanced Science, EarlyView.
A hierarchically selective immunotherapeutic nanoplatform, mGls@HEV‐MTP, selectively restores macrophage immunocompetence through GLS1‐mediated restoration of glutaminolysis‐fueled anaplerosis. Concurrently, it renders Staphylococcus aureus (S. aureus) more readily recognizable to the metabolically reprogrammed macrophages, thereby facilitating ...
Weinan Yang   +17 more
wiley   +1 more source

Zoliflodacin inhibits Streptococcus mutans biofilms

open access: yesFrontiers in Cellular and Infection Microbiology
Background Zoliflodacin (ZFD) is a new type of antibiotic whose anticaries potential through controlling biofilms remains unknown. This study aimed to explore the effects of ZFD on the conditional formation of cariogenic Streptococcus mutans (
Xu, Muxin   +8 more
openaire   +2 more sources

A Metal‐Polyphenol Self‐Assembled Coated 3D Sponge With Mild Photothermal Antibacterial, Exudate‐Controlling, and Immunomodulatory Functions for Hemostasis and Chronic Wound Healing

open access: yesAdvanced Science, EarlyView.
A thrombin‐functionalized copper‐polydopamine nanofiber sponge integrates rapid hemostasis, mild photothermal antibacterial therapy, stimulus‐responsive Cu2+ release, chemodynamic oxidative stress, and macrophage immunomodulation. This multifunctional dressing suppresses infection, regulates inflammation, promotes angiogenesis and re‐epithelialization,
Ziwei Zhang   +11 more
wiley   +1 more source

Single-walled carbon nanotubes as a nano-weapons against biofilm of Pseudomonas aeruginosa

open access: yesFrontiers in Microbiology
Background/introductionThe emergence of antimicrobial resistance in bacterial biofilms represents a growing global healthcare burden, necessitating the development of novel agents with alternative mechanisms of action.MethodsIn the present study, we ...
Majed Ahmed Al-Shaeri   +3 more
doaj   +1 more source

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

open access: yesAdvanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng   +8 more
wiley   +1 more source

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