Results 101 to 110 of about 475,267 (360)
PLoS Computational Biology, 2010 Every new scientific discipline or methodology reaches a point in its maturation where it is fruitful for it to turn its gaze inward, as well as backward. Such introspection helps to clarify the essential structure of a field of study, facilitating communication, pedagogy, standardization, and the like, while retrospection aids this process by ...
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Introduction to Bioinformatics
, 2019 How the scientific community looks at molecular biology today is very different from that 50 years ago. During this time technological developments have led to many significant findings that have shook one of the most important foundations of molecular biology: the central dogma.
AYYILDIZ, DILARA, Piazza S.
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Fungal Vaccine Development: State of the Art and Perspectives Using Immunoinformatics
Journal of Fungi, 2023 Fungal infections represent a serious global health problem, causing damage to health and the economy on the scale of millions. Although vaccines are the most effective therapeutic approach used to combat infectious agents, at the moment, no fungal ...
Moisés Morais Inácio +10 more
doaj +1 more source
Evaluation and comparison of bioinformatic tools for the enrichment analysis of metabolomics data
BMC Bioinformatics, 2018 Bioinformatic tools for the enrichment of ‘omics’ datasets facilitate interpretation and understanding of data. To date few are suitable for metabolomics datasets. The main objective of this work is to give a critical overview, for the first time, of the
Anna Marco-Ramell +6 more
semanticscholar +1 more source
mSystems, 2020 Method choice throughout the workflow of a microbiome study, from sample collection to DNA extraction and sequencing procedures, can greatly affect results.
Q. R. Ducarmon +4 more
semanticscholar +1 more source
Freedom in bioinformatics [PDF]
Frontiers in Genetics, 2014 1 Institut de Biologie Integrative et des Systemes, Universite Laval, Quebec City, QC, Canada 2 Departement de Biochimie, de Microbiologie et de Bio-informatique, Faculte des Sciences et de Genie, Universite Laval, Quebec City, QC, Canada 3 Centre de Recherche de l’Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec City, QC ...
Antony T Vincent +5 more
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
mAbs, 2020 The discovery of therapeutic monoclonal antibodies (mAbs) primarily focuses on their biological activity favoring the selection of highly potent drug candidates. These candidates, however, may have physical or chemical attributes that lead to unfavorable
Joschka Bauer +8 more
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Biology, 2022 Both the annotation and identification of genes in pathogenic parasites are still challenging. Although, as a survival factor, nitric oxide (NO) has been proven to be synthesized in Trichomonas vaginalis (TV), nitric oxide synthase (NOS) has not yet been
Hung-Che Lin +18 more
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