Results 251 to 260 of about 475,267 (360)

A framework for the safety evaluation of peptides in cosmetics. [PDF]

Curr Res Toxicol
Bjerke DL, Li J, Gao Y, Hu P, Lintner K, Hakozaki T.   +5 more
europepmc   +1 more source

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

Advanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu, Shuhao Chen, Yunheng Diao, Wei Wang, Yuanyuan Huang, Liqin Liang, Xiaodan Lu, Rui Han, Minxin Guo, Zhaobo Li, Shuhong Wang, Hehua Li, Chenyu Liu, Jing Zhou, Dongsheng Xiong, Xiaobo Li, Yuping Ning, Xuetao Shi, Fengchun Wu, Kai Wu   +19 more
wiley   +1 more source

Erratum: Discovering Novel Biomarkers Associated with the Pathogenesis of Psoriasis: Evidence from Bioinformatic Analysis [Corrigendum]. [PDF]

Int J Gen Med
europepmc   +1 more source

The Necessity of POMC and MC3R Analysis in the First-Level Diagnosis of Monogenic Obesity: The Experience of Two Italian Centers. [PDF]

Genes (Basel)
Miedviedieva K, Regoli T, Marchisotta S, Sessa L, Blasco M, Leanza S, Ciuoli C, Cantore A, Ricci C, Cantara S.   +9 more
europepmc   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Integrated Reanalysis of Global Riverine Fish eDNA Datasets Shows Robustness and Congruence of Biodiversity Conclusions. [PDF]

Mol Ecol
Zhang Y, Zhang H, Akashi H, Albouy CP, Andres KJ, Barquín J, Brantschen J, Connon RE, Craine JM, Gleeson D, Goldenberg-Vilar A, González-Ferreras AM, Hatzenbuhler C, Hupało K, Hyde J, Iwasaki W, Johnson MD, Katz AD, Kuzovlev VV, Larson CE, Lecaudey LA, Leese F, Leray M, Li F, Macher TH, Mauvisseau Q, Morán-Luis M, Nester G, Quintero H, Ravelomanana T, Chacko MR, Saccò M, Sales N, Schenekar T, Schletterer M, Schmidt S, Schulte NO, Schütz R, Sperry JH, Stevens ER, Stinson SA, Weiss S, Xia F, Zhang H, Zhang S, Zhong W, Zong S, Pellissier L, Zhang X, Altermatt F.   +49 more
europepmc   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source

The Potential of Bioinformatics in Revolutionizing Disease Diagnosis in Sub-Saharan Africa: A Narrative Review. [PDF]

Health Sci Rep
Ofosu W, Kotey FCN, Odoom A, Ntim OK, Donkor ES.   +4 more
europepmc   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Special Issue "Repetitive DNA". [PDF]

Int J Mol Sci
Šatović-Vukšić E, Garrido-Ramos MA, Plohl M.   +2 more
europepmc   +1 more source