Results 81 to 90 of about 475,267 (360)

A novel Cuprotosis-related signature predicts the prognosis and selects personal treatments for melanoma based on bioinformatics analysis

Frontiers in Oncology, 2023
BackgroundMelanoma is a common and aggressive cutaneous malignancy characterized by poor prognosis and a high fatality rate. Recently, due to the application of Immune–checkpoint inhibitors (ICI) in melanoma treatment, melanoma patients’ prognosis has ...
Bingqian Hu, Alphonse Houssou Hounye, Zheng Wang, Min Qi, Jianglin Zhang, Jianglin Zhang   +5 more
doaj   +1 more source

FungiDB: An Integrated Bioinformatic Resource for Fungi and Oomycetes

Journal of Fungi, 2018
FungiDB (fungidb.org) is a free online resource for data mining and functional genomics analysis for fungal and oomycete species. FungiDB is part of the Eukaryotic Pathogen Genomics Database Resource (EuPathDB, eupathdb.org) platform that integrates ...
E. Basenko, Jane A. Pulman, A. Shanmugasundram, O. Harb, K. Crouch, David Starns, Susanne Warrenfeltz, C. Aurrecoechea, C. Stoeckert, J. Kissinger, D. Roos, C. Hertz-Fowler   +11 more
semanticscholar   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Ironing out the conflicts: iron supplementation reduces negatives bacterial interactions in the rhizosphere of an Atacama-endemic perennial grass

Environmental Microbiome
Background In plants, root exudates selectively influence the growth of bacteria that colonize the rhizosphere. Bacterial communities associated with root systems are involved in macro and micronutrients cycling and organic matter transformation.
Constanza Aguado-Norese, Jonathan E. Maldonado, Christian Hodar, Gabriel Galvez, Daniel E. Palma, Verónica Cambiazo, Mauricio Gonzalez   +6 more
doaj   +1 more source

Best practices for bioinformatic characterization of neoantigens for clinical utility

Genome Medicine, 2019
Neoantigens are newly formed peptides created from somatic mutations that are capable of inducing tumor-specific T cell recognition. Recently, researchers and clinicians have leveraged next generation sequencing technologies to identify neoantigens and ...
Megan M. Richters, Huiming Xia, Katie M. Campbell, W. Gillanders, O. Griffith, M. Griffith   +5 more
semanticscholar   +1 more source

Synthetic-bioinformatic natural product antibiotics with diverse modes of action.

Journal of the American Chemical Society, 2020
Bacterial natural products have inspired the development of numerous antibiotics in use today. As resistance to existing antibiotics has become more prevalent, new antibiotic lead structures and activities are desperately needed.
J. Chu, Bimal Koirala, Nicholas Forelli, X. Vila-Farrés, Melinda A. Ternei, Thahmina Ali, Dominic A. Colosimo, S. Brady   +7 more
semanticscholar   +1 more source

New classifications for quantum bioinformatics: Q-bioinformatics, QCt-bioinformatics, QCg-bioinformatics, and QCr-bioinformatics

Briefings in Bioinformatics
Abstract Bioinformatics has revolutionized biology and medicine by using computational methods to analyze and interpret biological data. Quantum mechanics has recently emerged as a promising tool for the analysis of biological systems, leading to the development of quantum bioinformatics.
Majid Mokhtari, Samane Khoshbakht, Kobra Ziyaei, Mohammad Esmaeil Akbari, Sayyed Sajjad Moravveji   +4 more
openaire   +2 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Oncology and Pharmacogenomics Insights in Polycystic Ovary Syndrome: An Integrative Analysis

Frontiers in Endocrinology, 2020
Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovaries. Epidemiological findings revealed that women with PCOS are prone to develop certain cancer types due ...
Verónica Yumiceba, Andrés López-Cortés, Andrés López-Cortés, Andy Pérez-Villa, Iván Yumiseba, Santiago Guerrero, Jennyfer M. García-Cárdenas, Isaac Armendáriz-Castillo, Patricia Guevara-Ramírez, Paola E. Leone, Ana Karina Zambrano, César Paz-y-Miño   +11 more
doaj   +1 more source

A total crapshoot? Evaluating bioinformatic decisions in animal diet metabarcoding analyses

Ecology and Evolution, 2020
Metabarcoding studies provide a powerful approach to estimate the diversity and abundance of organisms in mixed communities in nature. While strategies exist for optimizing sample and sequence library preparation, best practices for bioinformatic ...
Devon R. O'Rourke, N. Bokulich, M. Jusino, M. MacManes, J. Foster   +4 more
semanticscholar   +1 more source