Results 121 to 130 of about 475,267 (360)

Low Expression of PLAT in Breast Cancer Infers Poor Prognosis and High Immune Infiltrating Level

International Journal of General Medicine, 2021
Xinyang Wang,1,* Dandan Xue,1,* Xiaoxia Zhu,2,* Rui Geng,3 Xin Bao,2 Xiang Chen,2 Tiansong Xia1,4 1Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, People’s Republic of China; 2Department ...
Wang X, Xue D, Zhu X, Geng R, Bao X, Chen X, Xia T   +6 more
doaj  

Patent Data for Comparative Study: Case study of Top Aspirants in Bioinformatics Industry

International Journal of Innovation, 2018
Innovation and technology are considered as a subject of success and achievement to the firm. The comparative study represents an essential procedure to identify the innovation and technological capabilities of major players involved in the ...
Neha Mago, Nishad Deshpande
doaj   +1 more source

Bioinformatic mapping of radical SAM-dependent RiPPs identifies new Cα, Cβ, and Cγ-linked thioether-containing peptides

Journal of the American Chemical Society, 2019
Recently developed bioinformatic tools have bolstered the discovery of ribosomally synthesized and posttranslationally modified peptides (RiPPs). Using an improved version of Rapid ORF Description & Evaluation Online (RODEO 2.0), a biosynthetic gene ...
Graham A. Hudson, Brandon J. Burkhart, Adam J DiCaprio, Christopher J. Schwalen, Bryce Kille, T. Pogorelov, D. Mitchell   +6 more
semanticscholar   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: an inter-laboratory study

bioRxiv, 2019
Background Antimicrobial resistance (AMR) poses a threat to public health. Clinical microbiology laboratories typically rely on culturing bacteria for antimicrobial susceptibility testing (AST).
R. Doyle, D. O’Sullivan, Sean Aller, Sebastian Bruchmann, T. Clark, A. Pelegrin, M. Cormican, E. D. Benavente, M. Ellington, E. McGrath, Y. Motro, Thi Phuong Thuy Nguyen, J. Phelan, L. Shaw, R. Stabler, A. van Belkum, L. van Dorp, N. Woodford, Jacob Moran-Gilad, J. Huggett, K. Harris   +20 more
semanticscholar   +1 more source

Bioinformatic approaches for genome finishing [PDF]

, 2011
Husemann P, Tauch A. Bioinformatic approaches for genome finishing.
Husemann, Peter, Tauch, Andreas
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

On Bioinformatic Resources

Genomics, Proteomics & Bioinformatics, 2015
A starting point of curating bioinformatic resources for the public is marked by the establishment of the US National Center for Biotechnology Information (NCBI) in 1988 [1]. One of its many purposes is certainly to echo the initiative of the Human Genome Project (HGP) –– when two landmark reports were published at the same time: “Mapping and ...
openaire   +3 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Determination of Physicochemical Properties of Human Immunoglobulin G- Fc Fragment by Bioinformatic

فصلنامه دانشگاه علوم پزشکی جهرم, 2021
Introduction: Immunoglobulins (Igs) are defensive glycoproteins specifically recognize and destroy pathogens. Immunoglobulin G (IgG) is most abundant Ig in serum has important protective role against infections. Fragment of crystallizable (Fc) in IgG has
Soheyla Rohani, Fatemeh Hajighasemi
doaj