Results 111 to 120 of about 475,267 (360)

Proteomic and Bioinformatic Analysis of mSWI/SNF (BAF) Complexes Reveals Extensive Roles in Human Malignancy

Nature Genetics, 2013
Subunits of mammalian SWI/SNF (mSWI/SNF or BAF) complexes have recently been implicated as tumor suppressors in human malignancies. To understand the full extent of their involvement, we conducted a proteomic analysis of endogenous mSWI/SNF complexes ...
Cigall Kadoch, D. Hargreaves, Courtney Hodges, Laura Elias, Lena Ho, J. Ranish, G. Crabtree   +6 more
semanticscholar   +1 more source

Bioinformatic analysis reveals the importance of epithelial-mesenchymal transition in the development of endometriosis

Scientific Reports, 2020
Background: Endometriosis is a frequently occurring disease in women, which seriously affects their quality of life. However, its etiology and pathogenesis are still unclear.
Meihong Chen, Yilu Zhou, Hong Xu, Charlotte N. Hill, R. Ewing, Deming He, Xiaoling Zhang, Yihua Wang   +7 more
semanticscholar   +1 more source

biomisc: collection of miscellaneous command line bioinformatic scripts [PDF]

, 2020
collection of miscellaneous command line bioinformatic ...
Olga Tsiouri
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Left ventricular assist device bioinformatics identify possible hubgenes and regulatory networks involved in the myocardium of patients with left ventricular assist device

Frontiers in Cardiovascular Medicine, 2022
ObjectiveThe aim of this study was to clarify the changes of myocardial gene expression profile after left ventricular assist device (LVAD) implantation and the related molecular biological significance.MethodsA thorough bioinformatic analysis to ...
Maryam Ajmal, Aisha Ajmal, Maryam Rizvi, Umar Salim, Lei Huang, Lei Huang, Lei Huang, Lei Huang   +7 more
doaj   +1 more source

Genetic Landscape of Prostate Cancer Conspicuity on Multiparametric Magnetic Resonance Imaging: A Systematic Review and Bioinformatic Analysis

European Urology Open Science, 2020
Context Multiparametric magnetic resonance imaging (mpMRI) detects most, but not all, clinically significant prostate cancer. The genetic basis of prostate cancer visibility and invisibility on mpMRI remains uncertain.
J. Norris, B. Simpson, M. Parry, C. Allen, R. Ball, A. Freeman, D. Kelly, Hyung L. Kim, A. Kirkham, S. You, V. Kasivisvanathan, H. Whitaker, M. Emberton   +12 more
semanticscholar   +1 more source

microRNA Bioinformatics

Cells, 2022
Firstly, I apologize for the delayed publication of this Special Issue in the form of a book title [...]
openaire   +3 more sources

TruncTrimmer: A First Step Towards Automating Standard Bioinformatic Analysis [PDF]

, 2021
Bioinformatic analysis is a time-consuming process for labs performing research on various microbiomes. Researchers use tools like Qiime2 to help standardize the bioinformatic analysis methods, but even large, extensible platforms like Qiime2 have ...
Lawless, Z. Gunner, Thompson, Dale R, Ricke, Steven C, Dittoe, Dana   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Identification of ibuprofen targeting CXCR family members to alleviate metabolic disturbance in lipodystrophy based on bioinformatics and in vivo experimental verification

Frontiers in Endocrinology
BackgroundLipodystrophy is a rare disease that is poorly diagnosed due to its low prevalence and frequent phenotypic heterogeneity. The main therapeutic measures for patients with clinical lipodystrophy are aimed at improving general metabolic ...
Zhiwen Cao, Zhiwen Cao, Yuxiao Zhao, Yuxiao Zhao, Ruixin Liu, Ruixin Liu, Xialin Yan, Jiqiu Wang, Jiqiu Wang, Na Chen   +9 more
doaj   +1 more source