Results 131 to 140 of about 9,447 (273)

Generation of Self-Organizing Macrovascular Constructs by Bioprinting Human iPSC-Derived Mesodermal Progenitor Cells. [PDF]

Adv Sci (Weinh)
ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Dogan LE, Chicaiza-Cabezas NA, Kleefeldt F, Wörsdörfer P, Groll J, Ergün S.   +5 more
europepmc   +2 more sources

Current Trends and Future Prospects of Integrating Electrospinning With 3D Printing Techniques for Mimicking Bone Extracellular Matrix Scaffolds

Journal of Polymer Science, Volume 63, Issue 6, Page 1481-1504, 15 March 2025.
ABSTRACT This article presents a review of the recent findings on the combination of electrospun nanofibers and three‐dimensional (3D)‐printed structures for extracellular matrix (ECM) scaffolds for bone tissue engineering. We explore the synergy between electrospinning (ES), which produces highly porous, fibrous structures from materials like collagen
Kardo Khalid Abdullah, Kolos Molnár
wiley   +1 more source

Microfluidic Capillary Arrays for Pixelated Control of Multimaterial Flows

Small, EarlyView.
A 3D‐printed pixellated capillary array maps up to thousands of fluid inputs into arbitrary multimaterial flow cross‐sections. Automated manifold design and laminar scaling are used to amplify printing resolution orders of magnitude, generating microscale fluidic control from printed elements, enabling designed microflows for potential use in ...
Max Chapman, Muhammad Utomo, David J. Collins   +2 more
wiley   +1 more source

Oral Microalgae‐Laden Hydrogels Modulating the Intestinal Microbiota Metabolism for Acute Alcohol‐Induced Liver Injury Therapy

Small, EarlyView.
A food‐grade microalgae‐laden hydrogel (FMH) enables efficient in situ microalgae cultivation and serves as an oral therapeutic platform for acute alcohol‐induced liver injury. FMH improves alcohol tolerance, alleviates oxidative stress, inflammation, and lipid metabolic disorders, restores gut microbial homeostasis, and provides synergistic ...
Zhixin Hu, Hongtao Wu, Xuanqi Liu, Xinxu Huang, Linli Jiang, Lei Liu, Xiaojie Li, Yawen Yao, Fengzheng Gao, Kui Zeng, Jiajing Zhou   +10 more
wiley   +1 more source

Binder Design in Extrusion‐Based 3D Printing of Electrodes: Enhancing Printability and Electrochemical Performance in Energy Storage Devices

Small, EarlyView.
Binder design plays a pivotal role in extrusion‐based 3D printing of energy storage electrodes by simultaneously governing ink printability and electrochemical performance. This review examines how diverse binder materials and design strategies are employed to enable printability while addressing key electrochemical challenges in energy storage devices,
Akesh Manimendra Badalge, Timothy J. Biddle, Huynh Tam Minh Nguyen, Eric Campbell, Munkhbayar Batmunkh, Tak Kim, Stefanie Feih, Yu Lin Zhong   +7 more
wiley   +1 more source

Bioprinting of insulin-producing multicellular aggregates with the pancreatic tissue-derived bioink

, 2020
Bioprinting technology enables directly incorporating multiple cells into complex 3D geometries by rapid and precise patterning to implement physiologically relevant architecture.
DONG, GYU HWANG, MYUNGJI, KIM, Song Cheol Kim, CHO, SEUNGYEON, KIMJAEWOOK, In kyoung Shim, JANG, JIN AH   +6 more
core  

Innovative 3D‐bioprinted microfibers in calcium phosphate cement platform with Nell‐1 to activate nerve‐bone axis for synergistic bone, vasculature, and nanofibrous nerve regeneration

Smart Molecules, EarlyView.
A 3D‐bioprinted platform with stem cells activates “nerve‐bone” signaling by enabling the spatiotemporal delivery of Nell‐1. This activation enhances neurovascular and bone regeneration through the CYFIP1 cascade. In rat calvarial defects, the platform doubled bone regeneration and nerve repair and tripled vascular density, resulting in superior ...
Minjia Zhu, Xinyi Li, Jingyi Li, Kan Yu, Zixiang Dai, Le Xiao, Qinrou Zhang, Zihan Jia, Qingchen Qiao, Zeqing Zhao, Ke Zhang, Yuxing Bai   +11 more
wiley   +1 more source

A composite bioink derived from lacrimal gland extracellular matrix and alginate

Journal of Applied Biomaterials & Functional Materials
With the high global prevalence of dry eye disease and around 17% attributed to aqueous deficient dry eye (ADDE), there is an urgent need for therapies targeting lacrimal gland (LG) insufficiency.
Luis Kasimir Leo, Katharina Elisabeth Wiebe-Ben Zakour, Julia Matros, Michael Christian Hacker, Florian Kai Groeber-Becker, Gerd Geerling, Joana Witt   +6 more
doaj   +1 more source

Optimization of Gelatin and Crosslinker Concentrations in a Gelatin/Alginate-Based Bioink with Potential Applications in a Simplified Skin Model

Molecules
Three-dimensional bioprinting allows for the fabrication of structures mimicking tissue architecture. This study aimed to develop a gelatin-based bioink for a bioprinted simplified skin model. The bioink printability and chemical-physical properties were
Aida Cavallo, Giorgia Radaelli, Tamer Al Kayal, Angelica Mero, Andrea Mezzetta, Lorenzo Guazzelli, Giorgio Soldani, Paola Losi   +7 more
doaj   +1 more source

Laponite Network Controls FGF‐2 Release and Drives Functional Nerve Regeneration via 3D‐Printed Nerve Wrap Interfaces

Small Methods, EarlyView.
We developed a 3D‐printed nerve interface integrating a biomimetic nanocomposite hydrogel with sustained delivery of thermostable FGF‐2. The bioactive interface supports Schwann cell activity and myelination while providing a regenerative microenvironment.
Diego N. Rodriguez‐Sanchez, Akshat Joshi, Saeed Safari, Leticia A. M. de Carvalho, Kevin S. Muller, Uijin Kim, Luciana P. Cartarozzi, Meenakshi Kamaraj, Menekse Ermis, Natan R. de Barros, Alexandre L. R. de Oliveira   +10 more
wiley   +1 more source