The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes
Brown fat cells burn lipids within their mitochondria to generate heat. This process involves two energy “shuttles,” one of which is naturally blocked during heat production. We found that the second shuttle (MASh) is not required to generate heat. However, when MASh is disabled, the fatty acids meant for fuel are instead converted back into stored fat.
Michaela Veliova +12 more
wiley +1 more source
Author Correction: Tree diversity is changing across tropical Andean and Amazonian forests in response to global change. [PDF]
Fadrique B +160 more
europepmc +1 more source
ABSTRACT Introduction Inhibitor development remains one of the most serious complications of replacement therapy in patients with hemophilia. Tumour necrosis factor‐alpha (TNF‐α) is a key pro‐inflammatory cytokine, and its genetic variants have been implicated in immune‐related conditions.
Alessandra Faustino da Conceição Bezerra +3 more
wiley +1 more source
Author Correction: Mechanism of BRCA1-BARD1 function in DNA end resection and DNA protection. [PDF]
Ceppi I +17 more
europepmc +1 more source
Exploration of inactive metabolic pathways in Antarctic <i>Pseudogymnoascus australis</i> through elicitation: a genomic and metabolomic approach to investigate its biotechnological potential. [PDF]
Leal K +8 more
europepmc +1 more source
Editorial: Multidrug resistant bacteria: new therapeutic approaches for a challenging problem. [PDF]
Fernández GC, Smani Y, Gómez SA.
europepmc +1 more source
Letter to the Editor regarding: "Pre- and post-analytical guidelines for the microscopic diagnosis of melanoma: recommendations from the Brazilian Society of Pathology" - Reply. [PDF]
Xavier-Júnior JCC +6 more
europepmc +1 more source

