Results 241 to 250 of about 176,199 (305)

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, Volume 16, Issue 2, Page 382-396, February 2026.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Congenital disorder of deglycosylation 2. Report of a novel <i>MAN2C1</i> pathogenic variant and additional phenotypic implications. [PDF]

Mol Genet Metab Rep
Aguirre-Guillen RL, Arredondo-Navarro LÁ, Hernández-Rodríguez MF, Eduardo MT, Del Rosario CPM, Arce-Lozoya MA, Ochoa-Padilla E, Rodríguez-Machuca VU.   +7 more
europepmc   +1 more source

Engineering a Perfusion Bioreactor System for hiPSC‐Derived Progenitor Co‐Culture Capturing Microglial Features in CNS Development

Biotechnology and Bioengineering, Volume 123, Issue 2, Page 363-378, February 2026.
The authors report the development of a controlled and scalable 3D co‐culture system combining hiPSC‐derived erythromyeloid progenitors and neurospheres within the Ambr® 250 Modular platform operated with a newly designed perfusion system. This model faithfully recapitulates early microglia–neural interactions, enabling progenitor integration ...
Catarina M. Gomes, Inês de Sá, Margarida Delgado, Paula M. Alves, Catarina Brito   +4 more
wiley   +1 more source

ERGA-BGE Genomes of Culex laticinctus, Culex modestus, Culex perexiguus, and Culex theileri: Unveiling the Genomes of the Key Vectors of West Nile Virus in the Mediterranean Basin. [PDF]

Genome Biol Evol
Ruiz-López MJ, Cebrián-Camisón S, Irisarri I, Magallanes S, Martínez-de la Puente J, Figuerola J, Waterhouse RM, Wellcome Sanger Institute Tree Of Life Management Samples And Laboratory Team, Wellcome Sanger Institute Scientific Operations Sequencing Operations, Wellcome Sanger Institute Tree Of Life Core Informatics Team, Haggerty L, Martin F, Brown T.   +12 more
europepmc   +1 more source

Biochemical Responses of Anopheles spp. Larvae to a Novel Brazilian BR101 Bacillus thuringiensis var. israelensis Formulation: Oxidative Stress, Detoxification Enzymes, and Safety for Nontarget Notonectidae and Gerridae Aquatic Insects

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
Bti BR101 exhibits strong larvicidal activity against Anopheles larvae spp., with dose‐dependent mortality and LC50 of 3.13 µg/mL. Bti increases ROS, lipid and protein oxidation, and activates antioxidant enzymes (SOD, CAT, GPx) and detoxification pathways (MFO and esterases), indicating moderate oxidative stress.
Izabel Cristina de Oliveira Bentes, Dayane Dantas Abensour, Maria Luiza Lima da Costa, Raquel Telles de Moreira Sampaio, Leticia Bernadete da Silva, Francisco Augusto da Silva Ferreira, Cláudia Patrícia da Silva Tavares, Hergen Vieira de Souza, Francisco de Assis Marque, Mário Antonio Navarro da Silva, Eduarda Andrade de Lima, Gislayne Trindade Vilas‐Boas, João Antonio Cyrino Zequi, André Correa de Oliveira, Rosemary Aparecida Roque   +14 more
wiley   +1 more source

The genomes sequenced for the neotropical stingless bees Scaptotrigona bipunctata and S. depilis strengthen the phylogenomics support for the taxonomy of social bees. [PDF]

Genet Mol Biol
Hofstatter PG, Freitas FCP, Luna-Lucena D, Campana L, Hartfelder K.   +4 more
europepmc   +1 more source

Genomic Resources for Imperiled Caribbean Reef‐Forming Corals (Hexacorallia: Scleractinia): Complete Mitochondrial Genomes of Dichocoenia stokesii, Diploria labyrinthiformis, Oculina patagonica, and Stephanocoenia intersepta

Ecology and Evolution, Volume 16, Issue 2, February 2026.
Mitochondrial genomes of imperiled Caribbean corals are sequenced. These genomic resources will support conservation initiatives. ABSTRACT Coral reefs provide a wide variety of services essential to both marine ecosystems and human societies yet reef‐forming corals are currently facing a multitude of global and local environmental stressors.
Katrina Zabransky, William Vuong, Stephanie M. Rosales, J. Antonio Baeza   +3 more
wiley   +1 more source

Global lessons from local contexts: The evolution of biomedicine education in Spain. [PDF]

PLoS One
Muñoz FJ, Esteban E, Pérez-Mediavilla A, Capitán L.   +3 more
europepmc   +1 more source

A Field‐Friendly, Non‐Toxic Fixative for Integrated Morphological and Molecular Research in Non‐Model Invertebrates

Ecology and Evolution, Volume 16, Issue 2, February 2026.
Formalin, ethanol, and RNAlater are commonly used fixatives for morphological and molecular studies, but each has limitations when specimen availability is low, as is often the case with field‐collected non‐model organisms. Here, we evaluate KINFix, a non‐toxic alcohol‐based fixative, in four invertebrate taxa and show that it effectively preserves ...
Irene del Olmo, Paula Moreno‐Martín, Patricia Álvarez‐Campos, Aida Verdes   +3 more
wiley   +1 more source