Propionate metabolism in a human pathogenic fungus: proteomic and biochemical analyses
Fungi of the complex Paracoccidioides spp. are thermodimorphic organisms that cause Paracoccidioidomycosis, one of the most prevalent mycoses in Latin America.
Luiz Paulo Araújo Santos +8 more
doaj +1 more source
Biologia molecular aplicada às dermatoses tropicais [PDF]
São apresentados conceitos básicos sobre célula, código genético e síntese protéica, e sobre algumas técnicas de biologia molecular, tais como PCR, PCR-RFLP, seqüenciamento de DNA, RT-PCR e immunoblotting. São fornecidos protocolos de extração de nucleotídeos e de proteínas, como salting out no sangue periférico e métodos do fenol-clorofórmio e do ...
openaire +3 more sources
Aplicació de tècniques proteòmiques de quantificació i validació en recerca biomèdica [PDF]
Les tècniques proteòmiques basades en l'espectrometria de masses (MS) permeten la caracterització de la complexa i dinàmica natura del proteoma. Aquestes eines han contribuit a entendre millor certes funcions biològiques i respostes cel·lulars i a ...
Colomé Calls, Núria +1 more
core +1 more source
Diabetes mellitus y barrera hematorretiniana. Análisis in vitro de la expresión de proteínas de tight junction y su traducción funcional. Implicaciones terapéuticas [PDF]
El edema macular diabético (DME) es una de las primeras causas de disminución de la agudeza visual en pacientes con retinopatía diabética (DR). La rotura de la barrera hematorretiniana (BHR) debido a la disrupción de las tight junctions (TJ) es el ...
Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular +1 more
core +1 more source
An in situ perfusion protocol of rat epididymal adipose tissue useful in metabolic studies
Experimental approaches involving the perfusion of tissues and organs offer the advantage of improved physiological relevance over the use of isolated tissues or cells while at the same time being much more controlled and tissue-specific than studies in ...
Gemma Cònsol +3 more
doaj +1 more source
Biologia molecular aplicada aos recursos genéticos. [PDF]
Este trabalho tem como objetivo descrever algumas das metodologias de biologia molecular utilizadas no Laboratório de Genética da Embrapa Amazônia Oriental (LABGEN) e Laboratório de Fitopatologia, visando à identificação, classificação e conservação de ...
BONFIM, K. +2 more
core
Biochemical data from the characterization of a new pathogenic mutation of human pyridoxine-5'-phosphate oxidase (PNPO) [PDF]
PNPO deficiency is responsible of severe neonatal encephalopathy, responsive to pyridoxal-5’-phosphate (PLP) or pyridoxine. Recent studies widened the phenotype of this condition and detected new genetic variants on PNPO gene, whose pathogenetic role and
Carducci, Carla +11 more
core +2 more sources
ACINUS: a putative integrant of programmed cell death in plants
Programmed cell death (PCD) is a key process for the maintaining of homeostasis in organisms, with a plethora of different types of PCD occurring in pluricellular organisms, such as apoptosis, ferroptosis, necroptosis and others. The response to stimulus
Felipe Castro Teixeira +6 more
doaj +1 more source
Electrocatalytic nanoparticle based sensing for diagnostics [PDF]
An early and accurate diagnosis is the key to the effective and ultimately successful treatment of a large number of diseases, and only sensitive detection methods allow an early diagnosis.
Maltez da Costa, Marisa +1 more
core +1 more source

