Results 241 to 250 of about 310,970 (312)

Small airway dysfunction as a functional barrier to spirometry-defined clinical remission in severe asthma treated with biologic therapies. [PDF]

World Allergy Organ J
Al-Ahmad M, Ali A, Talat W.
europepmc   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Biologics for Children and Adolescents with Asthma: A Systematic Review and Exploratory Indirect Comparative Analysis. [PDF]

J Asthma Allergy
Wu M, Li H, Geng H, Liu P, Wang C, Zhou L, Liu N, Li X, Zhi L.   +8 more
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Which drugs will Medicare negotiate next? Predicting selected drugs for Initial Price Applicability Year 2029. [PDF]

J Manag Care Spec Pharm
Li KH, Cousin EM, Sullivan SD.
europepmc   +1 more source

Generative AI and Clinicians Show Comparable Prognostic Reasoning From Clinical Narratives in Biologic-Treated CRSwNP. [PDF]

World J Otorhinolaryngol Head Neck Surg
Hack S, Kahn C, Garcia-Lliberos A, Rodriguez-Prado C, Biadsee A, Fieux M, Liu M, Glikson E, Takashima M, Ahmed OG, Sindwani R, Tang DM, Roxbury CR.   +12 more
europepmc   +1 more source

Bronchial Thermoplasty in Severe Asthma: Bridging Randomised and Real-World Evidence: A Systematic Review and Meta-Analysis. [PDF]

Adv Respir Med
Lúcio MJ, Pereira ML, Barata C, Lopes C, Aljazeeri J.   +4 more
europepmc   +1 more source

Inhaled corticosteroid adherence in the era of biologics for severe asthma. [PDF]

ERJ Open Res
Nolasco S, Crimi C.
europepmc   +1 more source

Short-term Outcomes of Polydioxanone Synthetic Mesh in 2-stage Breast Reconstruction: A Single-Center Comparative Study. [PDF]

Aesthet Surg J
Abbott EN, Li R, King D, Chumakov PE, Dash E, Kubiak CA, Braun SA, Gabriel A, Vucovich M, Mioton LM, Perdikis G.   +10 more
europepmc   +1 more source

From Precision Therapies to Imprecise Patient Selection: Are We Ready for Biologics in COPD? [PDF]

Open Respir Arch
Figueira-Gonçalves JM, Golpe R, de Miguel-Díez J.   +2 more
europepmc   +1 more source