Results 71 to 80 of about 643,896 (271)

Biologic treatments in Behçet’s disease

open access: yes, 2021
Behcet's disease (BD) significantly increases morbidity and mortality, especially in young men. While vascular involvement is the most frequent cause of mortality, ocular involvement, which can cause visual loss, is the most important cause of ...
Fatma Alibaz-Öner   +3 more
core   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

The tree width of auxiliary storage [PDF]

open access: yes, 2011
We propose a generalization of results on the decidability of emptiness for several restricted classes of sequential and distributed automata with auxiliary storage (stacks, queues) that have recently been proved.
Parlato, Gennaro   +3 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Scanning electron microscopic observations of fibrous structure of cemento-dentinal junction in healthy teeth

open access: yesIndian Journal of Dental Research, 2014
Introduction: The cemento-dentinal junction (CDJ) is a structural and biologic link between cementum and dentin present in the roots of teeth. Conflicting reports about the origin, structure and composition of this layer are present in literature.
B Pratebha, N D Jaikumar, R Sudhakar
doaj   +1 more source

Biologic Width: Evaluation and Correction of its Violation

open access: yesJournal of Oral Health and Community Dentistry, 2009
ABSTRACT The concept of Biologic Width has been widely described by periodontists and restorative dentists. An adequate understanding of relationship between periodontal tissues and restorative dentistry is paramount to ensure adequate form, function and esthetics, and comfort of the dentition.
Nikhil Sharma, Nitin Khuller
openaire   +1 more source

A nationwide student survey on biochemistry learning resources in Italy

open access: yesFEBS Open Bio, EarlyView.
We conducted a survey among Italian university students to investigate their preferred study materials for biochemistry. We then analyzed the collected data to identify these materials. This information may be valuable to the Biochemistry educational community. The graphical abstract was created with Claude (Opus 5.5; Anthropic, 2026).
Anna Marabotti   +4 more
wiley   +1 more source

An interhemispheric, statistical study of nightside spectral width distributions from coherent HF scatter radars [PDF]

open access: yes, 2002
International audienceA statistical investigation of the Doppler spectral width parameter routinely observed by HF coherent radars has been conducted between the Northern and Southern Hemispheres for the nightside ionosphere.
Milan, S. E.   +16 more
core   +2 more sources

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan   +5 more
wiley   +1 more source

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