Results 81 to 90 of about 2,836,469 (290)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Biological Activities of Phytochemicals in Plants

Turkish Journal of Agriculture: Food Science and Technology, 2020
Bioactive compounds, called phytochemicals, are produced as secondary metabolites in plants that have beneficial effects on health when they are consumed as nutrients.
Tuğba Demir, Özlem Akpınar
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Sustainable hunting tourism - business opportunity in Northern areas? Overview of hunting and hunting tourism in four Northern countries: Finland, Sweden, Iceland and Canada [PDF]

, 2007
The social sustainability and fluent co-operation with the interest groups is perhaps the most crucial issue related to the development of hunting tourism at the moment.
Anne, Matilainen (ed.)
core  

Biological Activity of Tropolone

Biological and Pharmaceutical Bulletin, 2003
Tropolone (1). showed strong insecticidal activity on Tyrophagus putrescentiae and Dermatophagoides farinae. The insecticidal effect of 1 on both insects was stronger than that of hinokitiol (2, 4-isopropyltropolone: major component of Thujopsis dolabrata SIEB. et ZUCC. hondai MAKINO). The insecticidal activity of both compounds was higher than that of
Yasuhiro, Morita, Eiko, Matsumura, Toshihiro, Okabe, Mitsunobu, Shibata, Masaaki, Sugiura, Tatsuhiko, Ohe, Hiroshi, Tsujibo, Nakao, Ishida, Yoshihiko, Inamori   +8 more
openaire   +3 more sources

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Nonclassical Biological Activities of Quinolone Derivatives

Journal of Pharmacy & Pharmaceutical Sciences, 2011
Quinolones are considered as a big family of multi-faceted drugs; their chemical synthesis is flexible and can be easily adapted to prepare new congeners with rationally devised structures.
Mohsen Daneshtalab, Abeer Ahmed
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Iridoids: Research Advances in Their Phytochemistry, Biological Activities, and Pharmacokinetics

Molecules, 2020
Iridoids are a class of active compounds that widely exist in the plant kingdom. In recent years, with advances in phytochemical research, many compounds with novel structure and outstanding activity have been identified.
Congcong Wang, Xue Gong, Agula Bo, Lei Zhang, Mingxu Zhang, Erhuan Zang, Chunhong Zhang, Minhui Li   +7 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source