Results 81 to 90 of about 403,543 (242)
Rekonstruktion und Analyse interzellulärer Signalnetzwerke [PDF]
, 2006 Skusa A. Reconstruction and analysis of intercellular signaling networks. Bielefeld (Germany): Bielefeld University; 2006.Cells in the human body communicate over long distances via two systems, the humoral system and the neuronal system.
Skusa, Andre
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Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Scientific ReportsSeveral studies have shown an association between prostate carcinoma (PCa) and Epstein-Barr virus (EBV); however, none of the studies so far have identified the histopathological and genetic markers of cancer aggressiveness associated with EBV in PCa ...
Khalid Ahmed +9 more
doaj +1 more source
Acceptance of biological evolution in first-year Life Sciences university students
, 2020 Lack of acceptance of biological evolution, despite the overwhelming evidence that support it, can be very problematic in higher education courses that have a strong biological basis.
Betti, Lia +2 more
core +1 more source
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
FEBS Open Bio, EarlyView.Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
Acanthamoeba and bacteria produce antimicrobials to target their counterpart
Parasites & Vectors, 2014 Background In the microbial ecosystem, microbes compete for space and nutrients. Consequently, some have developed the ability to kill or inhibit the growth of other competing microbes by producing antimicrobial substances.
Junaid Iqbal +2 more
doaj +1 more source
Peterson's Graduate Programs in the Biological/Biomedical Sciences & Health-Related/Medical Professions 2014 contains profiles of 6,750 graduate programs at over 1,280 institutions in the biological/biomedical sciences and health-related/medical ...
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Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Cellulose degradation: a therapeutic strategy in the improved treatment of Acanthamoeba infections
Parasites & Vectors, 2015 Acanthamoeba is an opportunistic free-living amoeba that can cause blinding keratitis and fatal brain infection. Early diagnosis, followed by aggressive treatment is a pre-requisite in the successful treatment but even then the prognosis remains poor.
Sahreena Lakhundi +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source