Results 141 to 150 of about 10,083,181 (394)

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Enhancing human pluripotent stem cell differentiation to cardiomyocytes through cardiac progenitor reseeding and cryopreservation

iScience
Summary: Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have the potential to transform the understanding of heart development and heart failure treatment.
Austin K. Feeney, Aaron D. Simmons, Claire J. Peplinski, Xiaotian Zhang, Sean P. Palecek   +4 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Evaluation of bone excision on occipital area of simulated human skull [PDF]

, 2016
Surgical effects of bone and soft tissue tumours, whether for biopsy or full excision have been researched from as early as the 1970’s [1]. These researches though have as main focus the biological (histological) rather the mechanical aspects of the
Adams, George John, Clasper, J., Franceskides, Constantinos, Horsfall, Ian, Leger, T., Shanker, Tobias, Zioupos, Peter   +6 more
core  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Thermal-biological aspects of germination of seeds in tropical forest tree species

, 2021
Luan Danilo Ferreira de Andrade Melo, João Luciano de Andrade Melo, Larice Bruna Ferreira Soares, Lívia Francyne Gomes Chaves, João Correia de Araújo Neto, Vilma Marques Ferreira, Maria Inajal Rodrigues da Silva das Neves, Edilma Pereira Gonçalves, Jeandson Silva Viana, Reinaldo de Alencar Paes, Jaqueline Figueredo de Oliveira Costa, Wesley Oliveira de Assis   +11 more
openalex   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Hydroxyapatite-bioglass nanocomposites: Structural, mechanical, and biological aspects. [PDF]

Beilstein J Nanotechnol, 2022
Shikimaka O, Bivol M, Sava BA, Dumitru M, Tardei C, Sbarcea BG, Grabco D, Pyrtsac C, Topal D, Prisacaru A, Cobzac V, Nacu V.   +11 more
europepmc   +1 more source

In vitro biological responses to nanofibrillated cellulose by human dermal, lung and immune cells: surface chemistry aspect [PDF]

, 2017
Viviana R. Lopes, Carla Sanchez-Martinez, Maria Strømme, Natália Ferraz   +3 more
openalex   +1 more source