Results 11 to 20 of about 1,734,368 (257)

Is Dosing of Ethambutol as Part of a Fixed-Dose Combination Product Optimal for Mechanically Ventilated ICU Patients with Tuberculosis? A Population Pharmacokinetic Study

Antibiotics, 2021
Background: Tuberculosis (TB) patients admitted to intensive care units (ICU) have high mortality rates. It is uncertain whether the pharmacokinetics of first-line TB drugs in ICU patients are different from outpatients.
Francisco Beraldi-Magalhaes, Suzanne L. Parker, Cristina Sanches, Leandro Sousa Garcia, Brenda Karoline Souza Carvalho, Mariana Millan Fachi, Marcus Vinicius de Liz, Roberto Pontarolo, Jeffrey Lipman, Marcelo Cordeiro-Santos, Jason A. Roberts   +10 more
doaj   +1 more source

Can Dietary Iron Bioavailability Influence Colorectal Cancer Risk and Prognosis? [PDF]

Middle East Journal of Cancer
Colorectal cancer (CRC) stands apart from other malignancies due to its pronounced association with dietary patterns. Approximately 70% of all CRC cases arise sporadically, and suboptimal dietary and lifestyle choices can override certain predisposing ...
Tara Rolić, Sanja Mandić, Iva Lukić, Ines Banjari   +3 more
doaj   +1 more source

Preparation and characterization of morphine gelatine microspheres

Designed Monomers and Polymers, 2023
Morphine is a widely used opioid analgesic. However, standard morphine dosages and administration methods exhibit a short half-life and pose a risk of respiratory depression.
Xin Jin, Jun Ji, Yonghai Sun
doaj   +1 more source

In vitro biopharmaceutical equivalence of drugs used in the treatment of tuberculosis in Peru [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Medicines are vital for public health, and it is essential to ensure their quality. This is especially important with multisource medications, which have not undergone clinical trials and may have limited bioavailability.
Luis A. Rodríguez-Hidalgo, Pedro M. Alva-Plasencia, Luis A. Concepción-Urteaga, Julio Hilario-Vargas, Olga E. Caballero-Aquiño, Vanessa Saldaña-Bobadilla, Amalia G. Vega-Fernandez   +6 more
doaj   +1 more source

Nutrient Interaction and Health Risk Assessment of Cereal Grains on Nigerian’s Markets

Journal of Food Quality and Hazards Control, 2022
Background: Cereals are the most staple foods in human diet and the main components of the daily diet. This work was designed to determine the level of essential and non-essential elements, the in vitro bioavailability, interrelationship, and associated ...
N.A. Obasi, S.E. Obasi, L.O. Ajala, G.O. Aloh, C. Aloke, S.S. Ogundapo, G.N. Onyeji   +6 more
doaj  

Albedo flour of Tahiti lime (Citrus latifolia Tanaka) as a strategy to control bone fragility in ovariectomized rats

Clinical Nutrition Open Science, 2021
Summary: Introduction: Experimental studies have shown that the albedo of Tahiti lime (Citrus latifolia Tanaka) is rich in calcium, but little is known about its bioavailability. Objective: Produce flour from the albedo of Tahiti lime, characterizing it
Pedro Henrique Costa Calmon Rodrigues, Savio Ernesto da Fonseca, Angela de Almeida Pretti Rocha, Paloma de Paula Pereira, Roberta Valeriano dos Santos, Girlandia Alexandre Brasil, Marcela Nascimento Sertorio, Christiane Mileib Vasconcelos   +7 more
doaj   +1 more source

An overview of the therapeutic applications of cinnamon-loaded in nanosystems [PDF]

Nanomedicine Journal
Cinnamon, a spice derived from the Cinnamomum genus, has a rich history of traditional medicinal applications. Its therapeutic potential arises from a diverse array of bioactive compounds exhibiting antioxidant, anti-inflammatory, and antimicrobial ...
Ali Asadi, BiBi Fatemeh Kalalinia, Somayeh Marouzi, Zahra Salmasi, Maryam Hashemi   +4 more
doaj   +1 more source

Relative bioavailability of three formulations of galunisertib administered as monotherapy in patients with advanced or metastatic cancer

Drugs in Context, 2016
Objective: Galunisertib (LY2157299 monohydrate), an inhibitor of the transforming growth factor β (TGFβ) pathway, is currently under investigation in several clinical trials involving multiple tumor types.
Ivelina Gueorguieva, Ann Cleverly, Durisala Desaiah, Analia Azaro, Joan Seoane, Irene Braña, Elisabet Sicart, Colin Miles, Michael M Lahn, Malcolm I Mitchell, Jordi Rodon   +10 more
doaj   +1 more source

Novel nanomicelle formulation to enhance bioavailability and stability of curcuminoids [PDF]

Iranian Journal of Basic Medical Sciences, 2019
Objective(s): Curcuminoids, comprising curcumin, demethoxycurcumin (DMC) and bisdemethoxycurcumin (BDMC), are bioactive phytochemicals with numerous pharmacological effects.
Mahdi Hatamipour, Amirhossein Sahebkar, Seyedeh Hoda Alavizadeh, Mahyar Dorri, Mahmoud Reza Jaafari   +4 more
doaj   +1 more source

The bioavailability of a paediatric sustained-action theophylline capsule

South African Family Practice, 1985
No abstract available.
R.S. Summers
doaj   +1 more source