Results 31 to 40 of about 358,862 (222)

Strategy in the Surgical Treatment of Primary Spinal Tumors

Global Spine Journal, 2012
Primary spine tumors are rare, accounting for only 4% of all tumors of the spine. A minority of the more common primary benign lesions will require surgical treatment, and most amenable malignant lesions will proceed to attempted resection. The rarity of
Richard Williams, Matthew Foote, Hamish Deverall   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Electromagnetic Fields, Oxidative Stress, and Neurodegeneration

International Journal of Cell Biology, 2012
Electromagnetic fields (EMFs) originating both from both natural and manmade sources permeate our environment. As people are continuously exposed to EMFs in everyday life, it is a matter of great debate whether they can be harmful to human health.
Claudia Consales, Caterina Merla, Carmela Marino, Barbara Benassi   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Differences between passport and biological (actual) age in the population of Russian patients suffering from arterial hypertension (analysis of the «Hyperion» register)

Терапевтический архив, 2018
The age of the patient is the most important factor determining the high risk of cardiovascular diseases. The subject of modern research was the study of the clinical role of the patient's biological age and its difference from passport age.
A G Arutyunov, A V Nozdrin, K B Shavgulidze, D S Tokmin, I V Osadchiy   +4 more
doaj   +3 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Study of the Biological Risk Factors for Fall in the Elderly Patients

Journal of the Indian Academy of Geriatrics, 2018
Objective: To assess the biological risk factors for fall in the elderly patients (≥ 60 years) presenting to the geriatric-medical OPD in a tertiary care hospital.
Neeta Bhardwaj, Manshi Kashyap
doaj  

The assessment of infection control in dental practices in the municipality of São Paulo

Brazilian Journal of Infectious Diseases
OBJECTIVE: The goal of this study was to evaluate the infection control measures actually implemented by dental surgeons during dental practice, as patients and professionals are exposed to high biological risk in dental care environments.
Jacqueline Kimiko Matsuda, Renato Satovschi Grinbaum, Harry Davidowicz   +2 more
doaj   +1 more source