Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1936
Annual report of the Marine Biological Laboratory in Woods Hole. 1936.
Marine Biological Laboratory (Woods Hole MA)
core
Assessment of clinical and biological characteristics by pathological subtypes of lung adenocarcinoma. [PDF]
Abe K +5 more
europepmc +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1961
Annual report of the Marine Biological Laboratory in Woods Hole. 1961.
Marine Biological Laboratory (Woods Hole MA)
core
Biological characteristics of ATP5A1 and its pathogenic mechanisms in human diseases: advances in clinical translation. [PDF]
Yuan SY +7 more
europepmc +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1915
Annual report of the Marine Biological Laboratory in Woods Hole. 1915.
Marine Biological Laboratory (Woods Hole MA)
core
Synthesis, Photophysical Properties, and Primary Biological Characteristics of Meso-pyrazole-substituted BODIPY Derivatives. [PDF]
Coşkun Z +5 more
europepmc +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source

