Results 81 to 90 of about 9,221,634 (266)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1890

open access: yes, 1890
Annual report of the Marine Biological Laboratory in Woods Hole. 1890.
Marine Biological Laboratory (Woods Hole MA)
core  

Identification, Biology, and Bactericide Control of Peach Bacterial Shot Hole in Hebei Province, China

open access: yesMicroorganisms
Peach bacterial shot hole is a major disease limiting the yield and quality in most peach-producing areas worldwide. To clarify its etiology and support the development of targeted management strategies, diseased samples were collected from Changli ...
Jianchao Cui   +10 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 2002

open access: yes, 2003
Annual report of the Marine Biological Laboratory in Woods Hole. 2002.
Marine Biological Laboratory (Woods Hole MA)
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1950

open access: yes, 1951
Annual report of the Marine Biological Laboratory in Woods Hole. 1950.
Marine Biological Laboratory (Woods Hole MA)
core  

Development and biological characterization of an infectious cDNA clone of NADC34-like PRRSV

open access: yesFrontiers in Microbiology
IntroductionPorcine Reproductive and Respiratory Syndrome virus (PRRSV) causes high abortion rates in gestating sows and stillbirths, as well as high piglet mortality, seriously jeopardizing the pig industry in China and worldwide.MethodsIn this study ...
Yafang Lin   +9 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Annual Report - Marine Biological Laboratory, 1941

open access: yes, 1942
Annual report of the Marine Biological Laboratory in Woods Hole. 1941.
Marine Biological Laboratory (Woods Hole MA)
core  

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