Results 51 to 60 of about 339,831 (263)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Functional agents to biologically control deoxynivalenol contamination in cereal grains

Frontiers in Microbiology, 2016
Mycotoxins, as microbial secondary metabolites, frequently contaminate cereal grains and pose a serious threat to human and animal health around the global.
Ye eTian, Yanglan eTan, Na eLiu, Yucai eLiao, Changpo eSun, Shuangxia eWang, Aibo eWu   +6 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

The problems of biopollution with jet fuels and the way of achieving solution [PDF]

Transport, 2008
The article considers and presents the classification methods of identifying and assessing petroleum biological contamination and techniques in maintaining biological stability of hydrocarbon fuel.
S. Boychenko, I. Shkilnuk, V. Turchak
doaj   +2 more sources

Crisis preparedness exercise on food and feed safety for IPA beneficiaries 2024

EFSA Journal
The European Food Safety Authority (EFSA) within the framework of the Preparatory measures for the participation of IPA beneficiaries in the European Food Safety Authority 2023–2026 will organize a total of 3 crisis preparedness training events for the ...
European Food Safety Authority (EFSA), Alberto Mancuso (Opera srl)   +1 more
doaj   +1 more source

Evaluation of Surface Hygiene of the Surrounding Objects in a University Hospital

Reabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija, 2020
Research background. Hygiene of the surfaces means a clean environment of a hospital, especially that of a patient, which consists of constant basic cleaning and disinfection.
Daiva Petruševičienė, Zita Gierasimovič, Greta Gailienė, Eglė Lendraitienė, Sigitas Mingaila   +4 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Bench‐Scale Performance Evaluation of Phosphonate (HEDP) for Corrosion Inhibition of Carbon Steel in a Power Plant Cooling Water System

Engineering Reports
Corrosion in circulating cooling water systems of power plants significantly compromises equipment reliability and energy efficiency. This study investigates the anticorrosive performance of 1‐hydroxyethylidene‐1,1‐diphosphonic acid (HEDP) on carbon ...
Olha Biedunkova, Pavlo Kuznietsov, Serhii Martynov, Alla Kucherova, Oleksandr Hrytsyna   +4 more
doaj   +1 more source

Biological Control of Aflatoxin in Maize Grown in Serbia

Toxins, 2020
Aspergillus flavus is the main producer of aflatoxin B1, one of the most toxic contaminants of food and feed. With global warming, climate conditions have become favourable for aflatoxin contamination of agricultural products in several European ...
Zagorka Savić, Tatjana Dudaš, Marta Loc, Mila Grahovac, Dragana Budakov, Igor Jajić, Saša Krstović, Tijana Barošević, Rudolf Krska, Michael Sulyok, Vera Stojšin, Mladen Petreš, Aleksandra Stankov, Jelena Vukotić, Ferenc Bagi   +14 more
doaj   +1 more source