Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Insect-specific viruses: transmission dynamics and biological control strategies against arboviruses. [PDF]
Wilkman L +5 more
europepmc +1 more source
A121 LACK OF CRP RESPONSE IN CROHN’S DISEASE ASSOCIATED WITH LOWER RATES OF BIOLOGIC THERAPY: RESULTS OF A SINGLE CENTER CASE-CONTROL STUDY [PDF]
Joshua Nero +3 more
openalex +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Biological Control of Root-Knot Nematodes, Meloidogyne javanica by Antagonistic Fungus Cladosporium sphaerospermum. [PDF]
El-Qurashi MA +2 more
europepmc +1 more source
ROLE OF CERTAIN BEAUVERIA BASSIANA (BALS.) ISOLATE AS BIOLOGICAL CONTROL AGENT AGAINST COWPEA APHID (Aphis craccivora koch) AND ITS EFFECT ON THE PREDATOR Chrysopela carnea (STEPHENS). [PDF]
M. Imam, Iman Imam
openalex +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Understanding the impacts of extreme weather on biological control through traveling wave analysis of a prey-predator model. [PDF]
Aktar MS +4 more
europepmc +1 more source

