Results 281 to 290 of about 22,316,568 (340)

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Encapsulation of Beauveria bassiana conidia as a new strategy for the biological control of Aedes aegypti larvae. [PDF]

Sci Rep
Bitencourt ROB, de Sousa Queiroz RR, Ribeiro A, de Souza Ribeiro YR, Boechat MSB, Carolino AT, Santa-Catarina C, Samuels RI.   +7 more
europepmc   +1 more source

Control of growth and squamous differentiation in normal human bronchial epithelial cells by chemical and biological modifiers and transferred genes.

, 1989
Andrea M. A. Pfeifer, J.F. Lechner, Tohru Masui, Roger R. Reddel, G E Mark, Curtis C. Harris   +5 more
openalex   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Interaction Effects of Farm-Scale Management of Natural Enemy Resources and the Surrounding Seminatural Habitat on Insect Biological Control. [PDF]

Insects
Lavandero B, Maldonado-Santos E, Muñoz-Quilodran E, González-Chang M, Zepeda-Paulo F, Salazar-Rojas Á, Villegas C.   +6 more
europepmc   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Thermal biology of Hypogeococcus pungens (Hemiptera: Pseudococcidae) explains its variable performance as a classical biological control agent for Harrisia martinii (Cactaceae) in Australia. [PDF]

Environ Entomol
Ezeh AE, Zalucki MP, Day MD, Taylor T, Furlong MJ.   +4 more
europepmc   +1 more source

Control of biologically active interleukin 2 messenger RNA formation in induced human lymphocytes.

, 1984
Shimon Efrat, Raymond Kaempfer
openalex   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Evaluation of Pupal Parasitoids <i>Trichomalopsis ovigastra</i> and <i>Pachycrepoideus vindemiae</i> as Potential Biological Control Agents of <i>Bactrocera dorsalis</i>. [PDF]

Insects
Teng Z, Wang Y, Jiang M, Zhang Y, Wang X, Wan F, Zhou H.   +6 more
europepmc   +1 more source