Results 71 to 80 of about 2,644,167 (321)
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Raport privind controlul calită܊ii microbiologice a produselor farmaceutice veterinare în anul 2013 [PDF]
Medicamentul Veterinar, 2014 The microbiological contamination of pharmaceutical products could have major consequences on the physical – chemical characteristics, safety and efficiency of the medicinal products and also on the out of specification products recall-associated costs ...
Simona Sturzu +4 more
doaj
MCA: Boolean Networks Control Algorithm [PDF]
arXiv, 2016 Control problem in a biological system is the problem of finding an interventional policy for changing the state of the biological system from an undesirable state, e.g. disease, into a desirable healthy state. Boolean networks are utilized as mathematical model for gene regulatory networks. This paper provides an algorithm to solve the control problem
arxiv
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
, 2020 Abstract Conservation biological control, implemented in the 1910s by erecting perches in rice fields for insectivorous birds, resulted in effective control of the fall armyworm. Guyana is supposed to be the first country where the tachinid parasitoid Lydella minense, which had been collected in 1932 in Brazil, was successfully introduced for ...
openaire +3 more sources
Molecular Oncology, EarlyView.The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens +8 more
wiley +1 more source
Delayed Feedback Control Requires an Internal Forward Model [PDF]
arXiv, 2009 Biological motor control provides highly effective solutions to difficult control problems in spite of the complexity of the plant and the significant delays in sensory feedback . Such delays are expected to lead to non trivial stability issues and lack of robustness of control solutions.
arxiv
Sequential Control of Boolean Networks with Temporary and Permanent Perturbations [PDF]
arXiv, 2020 Direct cell reprogramming makes it feasible to reprogram abundant somatic cells into desired cells. It has great potential for regenerative medicine and tissue engineering. In this work, we study the control of biological networks, modelled as Boolean networks, to identify control paths driving the dynamics of the network from a source attractor ...
arxiv
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source