Results 31 to 40 of about 29,021,689 (318)

Dissemination and visualisation of biological data

, 2023
With the recent advent of various waves of technological advances, the amount of biological data being generated has exploded. As a consequence of this data deluge, new challenges have emerged in the field of biological data management. In order to maximize the knowledge extracted from the huge amount of biological data produced it is of great ...
openaire   +4 more sources

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Synergistic efforts in specimen digitisation, curation and cataloguing of Brazil's megadiverse flora and funga

Plants, People, Planet
Societal Impact Statement Digital technology has brought a rapid global information exchange, impacting all areas of our lives. This also applies to science.
Ana Flávia Alves Versiane, Fabiana Ranzato Filardi, Thuane Bochorny, Paula Leitman, Mariana Taniguchi, Felipe Alves de Oliveira, Luís Alexandre Estevão daSilva, Rafael Oliveira Lima, Domingos Cardoso, Rafaela Campostrini Forzza   +9 more
doaj   +1 more source

Geoscience data publication: Practices and perspectives on enabling the FAIR guiding principles

Geoscience Data Journal, 2022
Introduced in 2016, the FAIR Guiding Principles endeavour to significantly improve the process of today's data‐driven research. The Principles present a concise set of fundamental concepts that can facilitate the findability, accessibility ...
Danie Kinkade, Adam Shepherd
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Bioinformatics Tools and Big Data Analytics for Understanding Agricultural Microbial Ecosystems

Applied Microbiology
Microbial diversity and sustainable agriculture are key players for the mutual harmony of the nature/agriculture ecosystem that align with the Sustainable Development Goals (SDGs).
Madan L. Verma, Meenu Thakur, Prachi Arora, Prince Sharma, Sarita Devi   +4 more
doaj   +1 more source

Linked data and provenance in biological data webs [PDF]

Briefings in Bioinformatics, 2009
The Web is now being used as a platform for publishing and linking life science data. The Web's linking architecture can be exploited to join heterogeneous data from multiple sources. However, as data are frequently being updated in a decentralized environment, provenance information becomes critical to providing reliable and trustworthy services to ...
Jun Zhao 0003, Alistair J. Miles, Graham Klyne, David M. Shotton   +3 more
openaire   +3 more sources

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Potential biomarkers of acute myocardial infarction based on weighted gene co-expression network analysis

BioMedical Engineering OnLine, 2019
Background Acute myocardial infarction (AMI) is the common cause of mortality in developed countries. The feasibility of whole-genome gene expression analysis to identify outcome-related genes and dysregulated pathways remains unknown.
Zhihua Liu, Chenguang Ma, Junhua Gu, Ming Yu   +3 more
doaj   +1 more source