Results 151 to 160 of about 1,542,489 (314)

Microbiology and atmospheric processes: Biological, physical and chemical characterization of aerosol particles [PDF]

open access: yes, 2008
The interest in bioaerosols has traditionally been linked to health hazards for humans, animals and plants. However, several components of bioaerosols exhibit physical properties of great significance for cloud processes, such as ice nucleation and cloud
R. Psenner   +18 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Other Analytical Methods for the Detection of Biological and Chemical Threats

open access: yes
Biological and chemical agents are threats that have harmful effects on living organisms. It is very important to monitor these effects, which can lead to death.
Timur S., Hanoglu S.B., Ucar N.
core   +1 more source

Computational analysis and learning for a biologically motivated model of boundary detection

open access: yes, 2008
International audienceIn this work we address the problem of boundary detection by combining ideas and approaches from biological and computational vision.
Faugeras, Olivier   +7 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

DNA methods for the detection of Phytophthora cinnamomi from soil

open access: yes, 2006
This project assesses two aspects of DNA detection of Phytophthora species from soil samples. Firstly, a nested PCR protocol was established with both primary and nested PCR specific for P. cinnamomi detection. PCR amplification of P.
Anderson, Nari Michelle
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Automatic detection of stress using biological signals

open access: yes, 2020
Bachelor's thesis is focused on stress detection. This thesis defines the concept of stress, analyzes the appropriate biological signals for stress detection, presents databases of biological signals, that were used for stress detection and mentions ...
Votýpka, Tomáš
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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