Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Gut microbial diversity and inferred capacity to produce short-chain fatty acids are associated with acute stress reactivity in healthy adults. [PDF]
Karner T +3 more
europepmc +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Phage Cocktail Designed for Wastewater Bioremediation Has Limited Effect on Crustacean Filtrator Microbiome Diversity and Health. [PDF]
Grabska M +4 more
europepmc +1 more source
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu +5 more
wiley +1 more source
Life as Counterfactual Geometry: An Adversarial Theory of Biological Function. [PDF]
Buzea CG +7 more
europepmc +1 more source
Exploring anatomical and geographical drivers of the microbiota in wild capybaras (Hydrochoerus hydrochaeris): Baseline Data for zoonotic risk assessment. [PDF]
Camargo M +10 more
europepmc +1 more source
Leveraging Microbe-Rhizosphere Interactions in Organic Farming Systems: A Route to Sustainable Soybean Production. [PDF]
Osuji IE, Akanmu AO, Babalola OO.
europepmc +1 more source
Scaling laws for function diversity and specialization across socioeconomic and biological complex systems. [PDF]
Yang VC +6 more
europepmc +1 more source
Large future genetic diversity losses are predicted from conservation indicators even with habitat protection. [PDF]
Mualim KS +5 more
europepmc +1 more source

