Results 151 to 160 of about 7,103,771 (354)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Biological Evolution of Castration-resistant Prostate Cancer.

open access: yesEuropean Urology Focus, 2019
Alastair Davies   +3 more
semanticscholar   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Evolutional Characterization of Photochemically Induced Stroke in Rats: a Multimodality Imaging and Molecular Biological Study [PDF]

open access: hybrid, 2016
Nai-Wei Liu   +13 more
openalex   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Publications of the exobiology program for 1983: A special bibliography [PDF]

open access: yes
A list of 1983 publications resulting from research pursued under the auspices of NASA's Exobiology Program is given. Topics in the fields of biological, chemical, and planetary evolution; geochemistry; and intelligent extraterrestrial life are ...
Devincenzi, D. L., Pleasant, L. G.
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Virulence is associated with daily rhythms in the within‐host replication of the malaria parasite Plasmodium chabaudi

open access: yesEvolutionary Applications
Most malaria (Plasmodium spp.) parasite species undergo asexual replication synchronously within the red blood cells of their vertebrate host. Rhythmicity in this intraerythrocytic developmental cycle (IDC) enables parasites to maximise exploitation of ...
Alíz T. Y. Owolabi   +2 more
doaj   +1 more source

Does the Scientific Progress Dispense the Teaching of Biological Evolution?

open access: diamond, 2015
Heslley Machado Silva   +2 more
openalex   +1 more source

Home - About - Disclaimer - Privacy