Results 151 to 160 of about 1,894,620 (286)

Cooperation and Competition Were Primary Driving Forces for Biological Evolution. [PDF]

Microb Physiol
Saier MH.
europepmc   +1 more source

How and why kinetics, thermodynamics, and chemistry induce the logic of biological evolution. [PDF]

Beilstein J Org Chem, 2017
Pross A, Pascal R.
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

The prebiotic emergence of biological evolution. [PDF]

R Soc Open Sci
Kocher CD, Dill KA.
europepmc   +1 more source

Chemical roots of biological evolution: the origins of life as a process of development of autonomous functional systems. [PDF]

Open Biol, 2017
Ruiz-Mirazo K, Briones C, de la Escosura A.   +2 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Prediction of biological evolution following blood product transfusion during liver transplantation: the contribution of machine learning to decision-making. [PDF]

BMJ Health Care Inform
Duranteau O, Popoff B, Abels A, Lucidi V, Savier E, Blanchard F, Martinez T, Loi P, Germanova D, Demulder A, Creteur J, Tuna T.   +11 more
europepmc   +1 more source

The virtue of innovation: innovation through the lenses of biological evolution. [PDF]

J R Soc Interface, 2015
Kell DB, Lurie-Luke E.
europepmc   +1 more source

Biological Innovation Leads to Biological Evolution

Survival is the sole purpose of living organisms. To survive, organisms must possess survival capabilities. Unlike non-living entities, autonomy is the core mechanism by which organisms uphold their purpose of survival and exert their survival abilities.
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source