Results 241 to 250 of about 5,578,660 (353)

Biological Feedbacks as Cause and Demise of Neoproterozoic Icehouse: Astrobiological Prospects for Faster Evolution and Importance of Cold Conditions

, 2007
P. Janhunen, Hermanni Kaartokallio, Ilona Oksanen, Kirsi Lehto, H. J. Lehto   +4 more
openalex   +2 more sources

Trace elements at the intersection of marine biological and geochemical evolution

, 2016
L. Robbins, S. Lalonde, N. Planavsky, C. Partin, C. Reinhard, B. Kendall, C. Scott, D. Hardisty, Benjamin C Gill, D. Alessi, C. Dupont, M. Saito, S. Crowe, S. Poulton, A. Bekker, T. Lyons, K. Konhauser   +16 more
semanticscholar   +1 more source

Randomness Increases Order in Biological Evolution

Computation, Physics and Beyond, 2012
G. Longo, Maël Montévil
semanticscholar   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

The cosmological model of eternal inflation and the transition from chance to biological evolution in the history of life: The possibility of chance emergence of the replication and translation systems, and the protein superfolds

, 2007
Eugene V. Koonin
openalex   +2 more sources

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

An adaptive dynamics framework for microbial ecology and evolution. [PDF]

Sci Rep
Karlsson CJ, Gerlee P, Rowlett J.
europepmc   +1 more source

3P297 In Vivo molecular imaging revealed adipose tissue malfunction and remodeling in obesity(Bioimaging. The genesis of life, and biological evolution,Oral Presentations)

, 2007
Satoshi Nishimura
openalex   +2 more sources

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

From friend to foe and back: coevolutionary transitions in the mutualism-antagonism continuum. [PDF]

Proc Biol Sci
Jäger F, Schurr FM, Allhoff KT.
europepmc   +1 more source