Results 241 to 250 of about 1,840,126 (315)

3P297 In Vivo molecular imaging revealed adipose tissue malfunction and remodeling in obesity(Bioimaging. The genesis of life, and biological evolution,Oral Presentations)

, 2007
Satoshi Nishimura
openalex   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Planetary microbiology: microbes, planets, and the search for life. [PDF]

Appl Environ Microbiol
Kaçar B.
europepmc   +1 more source

Horizontal Gene Transfer among Bacteria and Its Role in Biological Evolution. [PDF]

Life (Basel), 2014
Arber W.
europepmc   +1 more source

3P269 Conformational Free Energy Landscapes in Sequence Space for a Certain Protein Conformation(The genesis of life, and biological evolution,Poster Presentations)

, 2007
Takuyo Aita, Yuzuru Husimi
openalex   +2 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Abiotic environmental conditions determine phage resistance outcomes in a salt-marsh bacterium. [PDF]

Philos Trans R Soc Lond B Biol Sci
Silk E, Harding K, Mahler M, Fineran PC, Meaden S.   +4 more
europepmc   +1 more source

3P317 Real time quantitation of the endogenous mRNA in single living cells(Bioimaging. The genesis of life, and biological evolution,Oral Presentations)

, 2007
Kohki Okabe, Takashi Funatsu, Yoshie Harada   +2 more
openalex   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Towards a mathematical framework for modelling cell fate dynamics. [PDF]

J Math Biol
Vittadello ST, Diaz L, Liu Y, Zanca A, Stumpf MPH.   +4 more
europepmc   +1 more source