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Directed Evolution: Methodologies and Applications

Chemical Reviews, 2021
Directed evolution aims to expedite the natural evolution process of biological molecules and systems in a test tube through iterative rounds of gene diversifications and library screening/selection.
Ye Li, Mingfeng Cao, Pu Xue
exaly   +2 more sources

Pre-biological evolution [PDF]

open access: possibleActa Biotheoretica, 1968
Some theoretical examples of possibilities for natural selection in a prebiotic organic medium at the molecular level are given. These examples, presented in the form of simple kinetic models, are based on the idea that the occurrence of autocatalysis and self-duplication broke through the limitations imposed by contacts by chance with rare but ...
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Equations for biological evolution

Proceedings of the Royal Society of Edinburgh: Section A Mathematics, 1995
In this paper we consider mathematical models inspired by the mechanisms of biological evolution. We take populations which are subject to interaction and mutation. In the cases we consider, the interaction is through competition or through a prey-predator relationship. The models consider the specific characteristics as taking values in real intervals
Àngel Calsina, Carles Perelló
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Biological evolution

Oxford Scholarship Online, 2018
The chapter discusses the history of life on Earth, and the lessons to be learned from the neo-Darwinian synthesis of evolutionary biology. The long and complex sequence of events in the evolutionary history of life on Earth requires considered ...
Andrew Briggs, Hans Halvorson, A. Steane
semanticscholar   +1 more source

History and Biological Evolution

Philosophy of Science, 1941
What is the relationship of history to the phylogenetic evolution of man? Historians, like all specialists, are wont to restrict themselves to their own problems and, therefore, do not deal with this question. Only some popular books on the history of the world cross the dividing line between social and natural science.
Edgar Zilsel   +3 more
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A mathematical model of biological evolution

Journal of Mathematical Biology, 1982
In order to understand generally how the biological evolution rate depends on relevant parameters such as mutation rate, intensity of selection pressure and its persistence time, the following mathematical model is proposed: dNn(t)/dt = (mn(t) - mu)Nn(t) + muNn-1(t) (n = 0,1,2,3,...), where Nn(t) and mn(t) are respectively the number and Malthusian ...
N. Ogita   +2 more
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On the thermodynamics of biological evolution

Journal of Theoretical Biology, 1978
Abstract A theory is proposed which explains the peculiarities of biological evolution on the basis of classical thermodynamics. Notions are introduced of particular evolutions as components of the general evolution of the biosphere. Thermodynamic criteria of evolutions are formulated allowing experimental proof of the applicability of classical ...
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