Results 171 to 180 of about 4,859,991 (300)

Digital pathways connecting social and biological factors to health outcomes and equity. [PDF]

NPJ Digit Med
Cui Y.
europepmc   +1 more source

The complex interplay between psychosocial and biological factors in pregorexia nervosa - a rapid review. [PDF]

Front Psychol, 2023
Vasiliu O.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Socioeconomic inequalities in childhood and adolescent obesity in Australia: The role of behavioral and biological factors. [PDF]

PLoS One
Gautam N, Chowdhury A, Rahman MM, Khanam R.   +3 more
europepmc   +1 more source

Metabolic syndrome in adults with autistic traits: associated psychological, behavioral, and biological factors in females and males - a PharmLines initiative. [PDF]

Front Psychiatry, 2023
Warreman EB, Nooteboom LA, Leenen PJM, Geurts HM, Terry MB, Bos JHJ, Hak E, Hoek HW, van Rossum EFC, Vermeiren RRJM, Ester WA.   +10 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Factors Controlling Biological Multiplication [PDF]

Nature, 1954
openaire   +1 more source

Serum Concentrations of Selected Biological Factors as a Potential Tool for Detecting Recurrence in Endocrine Tumors-A Pilot Study. [PDF]

J Clin Med
Kurzynska A, Przybylik-Mazurek E, Morawiec-Slawek K, Kolasa M, Tkacz E, Stefanska A, Szuminska M, Sowa-Staszczak A, Brodowicz J, Gawlik K, Pawlica-Gosiewska D, Solnica B, Hubalewska-Dydejczyk A, Opalinska M.   +13 more
europepmc   +1 more source

Biological factors and statistical limitations prevent detection of most noncanonical proteins by mass spectrometry. [PDF]

PLoS Biol, 2023
Wacholder A, Carvunis AR.
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source